Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1776278 | 0.99 | TSHR (0.42) | TSHRALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1776012 | 0.81 | GUSB (0.43) | — | |
| SCHEMBL1776299 | 0.81 | TDP1 (0.44) | TSHRALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1775921 | 0.80 | GUSB (0.42) | — | |
| Hydrochloric Acid SCHEMBL1775588 | 0.80 | TDP1 (0.43) | TSHRALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1775535 | 0.74 | FLT3 (0.46) | KMT2AGAA | |
| SCHEMBL1775401 | 0.73 | HRH4 (0.45) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5015937 | 0.73 | HRH4 (0.46) | ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL1773881 | 0.73 | FLT3 (0.45) | KMT2AGAA | |
| SCHEMBL1775441 | 0.73 | HTR6 (0.45) | L3MBTL1SMN1; SMN2NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |