Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 7/20 | 0.44 |
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1774702 | 0.99 | HRH4 (0.44) | HRH4LMNAPKMSMN1; SMN2HTR6 | |
| SCHEMBL1775441 | 0.91 | HTR6 (0.45) | HRH4SMN1; SMN2HTR6HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL1775491 | 0.90 | HTR6 (0.45) | HRH4SMN1; SMN2HTR6HTR2AHTR1A | |
| SCHEMBL1774608 | 0.89 | HTR6 (0.51) | LMNAHTR6HTR2AHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL1775137 | 0.88 | HTR6 (0.50) | LMNAHTR6HTR2AHTR1AHTR7 | |
| SCHEMBL1777202 | 0.87 | HTR6 (0.48) | LMNAHTR6HTR2AHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL1775919 | 0.86 | HTR6 (0.47) | LMNAHTR6HTR2AHTR1AHTR7 | |
| SCHEMBL1776834 | 0.83 | LMNA (0.43) | LMNAHTR6HTR2AHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL1775206 | 0.82 | LMNA (0.42) | LMNAHTR6HTR2AHTR1AHTR7 | |
| SCHEMBL5015937 | 0.81 | HRH4 (0.46) | HRH4HTR2AHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |