Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17746137 | 1.00 | KDM4E (0.45) | KDM4EL3MBTL1ATMESR1CYP19A1 | |
| SCHEMBL10128529 | 0.86 | KDM4E (0.50) | KDM4EL3MBTL1ATMESR1CYP19A1 | |
| SCHEMBL19831919 | 0.85 | KDM4E (0.49) | KDM4EL3MBTL1ATMESR1CYP19A1 | |
| SCHEMBL9890960 | 0.82 | KDM4E (0.46) | KDM4EL3MBTL1ATMESR1CYP19A1 | |
| SCHEMBL17124535 | 0.82 | PTGS2 (0.49) | KDM4EL3MBTL1ATMESR1PTGS2 | |
| SCHEMBL12774537 | 0.81 | KDM4E (0.45) | KDM4EL3MBTL1ATMESR1CYP19A1 | |
| SCHEMBL14798344 | 0.81 | L3MBTL1 (0.45) | KDM4EL3MBTL1ATMESR1CYP19A1 | |
| SCHEMBL14124332 | 0.79 | KDM4E (0.53) | KDM4EL3MBTL1ATMESR1CYP19A1 | |
| SCHEMBL17746160 | 0.79 | KDM4E (0.64) | KDM4EL3MBTL1ATMCYP19A1PTPN1 | |
| SCHEMBL17714718 | 0.78 | PTPN1 (0.41) | KDM4EL3MBTL1ATMESR1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10770663-B2 | Germanium-centered dendrimer compound, and organic optoelectric element comprising same | CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2020-09-08 | — | — | US | disclosed |
| US-20160141520-A1 | GERMANIUM-CENTERED DENDRIMER COMPOUND, AND ORGANIC OPTOELECTRIC ELEMENT COMPRISING SAME | CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10770663-B2 | Germanium-centered dendrimer compound, and organic optoelectric element comprising same | GRK1, OCIAD2, CD40LG | KDM4E 4231/4885L3MBTL1 1759/4885ATM 2529/4885 |
| US-20160141520-A1 | GERMANIUM-CENTERED DENDRIMER COMPOUND, AND ORGANIC OPTOELECTRIC ELEMENT COMPRISING SAME | GRK1, OCIAD2, CD40LG | KDM4E 4231/4885L3MBTL1 1759/4885ATM 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.