Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12774537 | 0.99 | KDM4E (0.45) | KDM4EATML3MBTL1CYP19A1CYP11B2 | |
| SCHEMBL10128529 | 0.93 | KDM4E (0.50) | KDM4EATML3MBTL1CYP19A1CYP11B2 | |
| SCHEMBL12774519 | 0.92 | KDM4E (0.45) | KDM4EATML3MBTL1CYP19A1CYP11B2 | |
| SCHEMBL12774549 | 0.91 | KDM4E (0.44) | KDM4EATML3MBTL1CYP19A1CYP11B2 | |
| SCHEMBL13513198 | 0.89 | ATM (0.40) | KDM4EATML3MBTL1CYP19A1CYP11B2 | |
| SCHEMBL19831919 | 0.89 | KDM4E (0.49) | KDM4EATML3MBTL1CYP19A1CYP11B2 | |
| SCHEMBL76484 | 0.85 | CYP19A1 (0.53) | KDM4ECYP19A1CYP11B2PTGS2ESR1 | |
| SCHEMBL29416717 | 0.85 | CYP19A1 (0.53) | KDM4ECYP19A1CYP11B2PTGS2ESR1 | |
| SCHEMBL4826058 | 0.83 | CYP19A1 (0.52) | KDM4ECYP19A1CYP11B2KMT2APTGS2 | |
| SCHEMBL13168405 | 0.83 | KDM4E (0.37) | KDM4EATML3MBTL1CYP19A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120138907-A1 | LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE | TORAY INDUSTRIES, INC. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20120138907-A1 | LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE | TORAY INDUSTRIES, INC. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-8084146-B2 | Light-emitting device material and light-emitting device | TORAY INDUSTRIES, INC. (JP) | 2011-12-27 | — | — | US | disclosed |
| US-8084146-B2 | Light-emitting device material and light-emitting device | TORAY INDUSTRIES, INC. (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20110049482-A1 | Novel aromatic compound and organic electroluminescent element containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20110049482-A1 | Novel aromatic compound and organic electroluminescent element containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-03-03 | — | — | US | disclosed |
| US-7790892-B2 | Aromatic compound and organic electroluminescent element containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-09-07 | — | — | US | disclosed |
| US-7790892-B2 | Aromatic compound and organic electroluminescent element containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-09-07 | — | — | US | disclosed |
| US-7651787-B2 | Organic electroluminescent device | LG DISPLAY CO., LTD. (KR) | 2010-01-26 | — | — | US | disclosed |
| US-7651787-B2 | Organic electroluminescent device | LG DISPLAY CO., LTD. (KR) | 2010-01-26 | — | — | US | disclosed |
| US-20070247063-A1 | Light-Emitting Device Material and Light-Emitting Device | TORAY INDUSTRIES INC. (JP) | 2007-10-25 | — | — | US | disclosed |
| US-20070247063-A1 | Light-Emitting Device Material and Light-Emitting Device | TORAY INDUSTRIES INC. (JP) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120138907-A1 | LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE | CRY1, MMS19, CRY2 | KDM4E 3391/4885ATM 600/4885L3MBTL1 167/4885 |
| US-20070247063-A1 | Light-Emitting Device Material and Light-Emitting Device | CRY1, CRY2, ATXN10 | KDM4E 3893/4885ATM 1395/4885L3MBTL1 530/4885 |
| US-20110049482-A1 | Novel aromatic compound and organic electroluminescent element containing the same | TYR, EML4, TCF7L2 | KDM4E 605/4885ATM 891/4885L3MBTL1 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.