Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808620 | 0.82 | GABRA1 (0.58) | GABRA1GABRB2FAAHPNMTPTGS2 | |
| SCHEMBL6914100 | 0.81 | ESR1 (0.37) | PTGS2PTGS1ESR1TSHRKMT2A | |
| SCHEMBL19491783 | 0.79 | GABRA1 (0.46) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL30151579 | 0.79 | GABRA1 (0.46) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL20875725 | 0.78 | GABRA1 (0.44) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL27864666 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2FAAHPTGS2PTGS1 | |
| SCHEMBL7562470 | 0.77 | GABRA1 (0.50) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL932599 | 0.77 | TTR (0.47) | GABRA1GABRB2ALOX15ALOX12NR3C1 | |
| SCHEMBL20875726 | 0.77 | GABRA1 (0.43) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL3074890 | 0.77 | GABRA1 (0.43) | GABRA1GABRB2PTGS2PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218341-B1 | PHENYL BASED COMPOUNDS SUBSTITUTED WITH ALDEHYDE MOIETIES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2024-05-01 | — | — | EP | disclosed |
| US-RE49502-E1 | Phenyl based compounds substituted with aldehyde moieties and their use in perfumery | GIVAUDAN SA (CH) | 2023-04-25 | — | — | US | disclosed |
| CN-107074713-B | Phenyl-based compounds substituted with aldehyde moieties and their use in perfumery | 奇华顿股份有限公司 | 2021-03-26 | — | — | CN | disclosed |
| US-10760033-B2 | Process of forming 2-(4-isobutyl-2-methylphenyl) propanal | GIVAUDAN SA (CH) | 2020-09-01 | — | — | US | disclosed |
| US-10443018-B2 | Phenyl based compounds substituted with aldehyde moieties and their use in perfumery | GIVAUDAN S.A. (CH) | 2019-10-15 | — | — | US | disclosed |
| EP-3089956-B1 | PROCESS | GIVAUDAN SA (CH) | 2019-08-07 | — | — | EP | disclosed |
| US-20180282662-A1 | Process | GIVAUDAN S.A. (CH) | 2018-10-04 | — | — | US | disclosed |
| US-20170298291-A1 | Phenyl Based Compounds Substituted with Aldehyde Moieties and their Use in Perfumery | GIVAUDAN S.A. (CH) | 2017-10-19 | — | — | US | disclosed |
| EP-3218341-A1 | PHENYL BASED COMPOUNDS SUBSTITUTED WITH ALDEHYDE MOIETIES AND THEIR USE IN PERFUMERY | Givaudan S.A. (CH) | 2017-09-20 | — | — | EP | disclosed |
| EP-3089956-A1 | PROCESS | Givaudan S.A. (CH) | 2016-11-09 | — | — | EP | disclosed |
| WO-2016075257-A1 | PROCESS | GIVAUDAN SA (CH) | 2016-05-19 | — | — | WO | disclosed |
| WO-2016074118-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2016-05-19 | — | — | WO | disclosed |
| WO-2016074865-A1 | PHENYL BASED COMPOUNDS SUBSTITUTED WITH ALDEHYDE MOIETIES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2016-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10760033-B2 | Process of forming 2-(4-isobutyl-2-methylphenyl) propanal | RNF168, RNF4, NFKB2 | GABRA1 203/4885GABRB2 77/4885FAAH 2529/4885 |
| US-10443018-B2 | Phenyl based compounds substituted with aldehyde moieties and their use in perfumery | C5, C9, CBR3 | GABRA1 2621/4885GABRB2 2474/4885FAAH 195/4885 |
| US-20180282662-A1 | Process | CUL4B, RNF10, BICRA | GABRA1 53/4885GABRB2 20/4885FAAH 3010/4885 |
| US-20170298291-A1 | Phenyl Based Compounds Substituted with Aldehyde Moieties and their Use in Perfumery | C5, C9, CBR3 | GABRA1 2621/4885GABRB2 2474/4885FAAH 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.