Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17633836 | 0.86 | MEN1 (0.54) | GBA1CASP2MEN1KMT2ATSHR | |
| SCHEMBL20920841 | 0.85 | GBA1 (0.41) | GBA1CASP2MEN1KMT2ATSHR | |
| SCHEMBL16405256 | 0.85 | CASP2 (0.60) | GBA1CASP2TSHRHPGDNAAA | |
| SCHEMBL12673157 | 0.83 | CASP2 (0.61) | CASP2MEN1KMT2AHPGDHDAC3 | |
| SCHEMBL20920850 | 0.82 | GBA1 (0.41) | GBA1CASP2MEN1KMT2ATSHR | |
| SCHEMBL24533703 | 0.81 | KMT2A (0.54) | GBA1MEN1KMT2ATSHRHPGD | |
| SCHEMBL16405258 | 0.80 | GBA1 (0.47) | GBA1CASP2TSHRHPGDHDAC3 | |
| SCHEMBL14976750 | 0.79 | CASP2 (0.57) | GBA1CASP2HPGDHDAC3HDAC1 | |
| SCHEMBL14241913 | 0.79 | MEN1 (0.56) | GBA1MEN1KMT2ATSHRHPGD | |
| SCHEMBL7780945 | 0.79 | CASP2 (0.48) | GBA1CASP2TSHRHPGDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266809-B2 | Polymer suitable for use in cell culture | STICHTING KATHOLIEKE UNIVERSITEIT (NL) | 2019-04-23 | — | — | US | disclosed |
| US-20160137977-A1 | POLYMER SUITABLE FOR USE IN CELL CULTURE | STICHTING RADBOUD UNIVERSITEIT (NL) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137977-A1 | POLYMER SUITABLE FOR USE IN CELL CULTURE | F13B, CD40, EPCAM | GBA1 4664/4885CASP2 3255/4885MEN1 1297/4885 |
| US-10266809-B2 | Polymer suitable for use in cell culture | F13B, CD40, EPCAM | GBA1 4664/4885CASP2 3255/4885MEN1 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.