Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16405245 | 0.87 | GBA1 (0.45) | GBA1CASP2ALDH1A1TSHRCNR1 | |
| SCHEMBL14752411 | 0.86 | CASP2 (0.46) | GBA1CASP2ALDH1A1CNR1HPGD | |
| SCHEMBL18874843 | 0.85 | GBA1 (0.46) | GBA1CASP2ALDH1A1TSHRHPGD | |
| SCHEMBL16407986 | 0.84 | GBA1 (0.43) | GBA1CASP2ALDH1A1TSHRCNR1 | |
| SCHEMBL22338220 | 0.82 | TSHR (0.45) | GBA1ALDH1A1TSHRHPGDPSMB5 | |
| SCHEMBL8847608 | 0.81 | CNR1 (0.57) | CASP2ALDH1A1CNR1HPGDPSMB5 | |
| SCHEMBL16405256 | 0.80 | CASP2 (0.60) | GBA1CASP2ALDH1A1TSHRCNR1 | |
| SCHEMBL17752144 | 0.80 | GBA1 (0.50) | GBA1CASP2TSHRHPGDHDAC3 | |
| SCHEMBL25083274 | 0.80 | TSHR (0.40) | GBA1ALDH1A1TSHRCNR1LMNA | |
| SCHEMBL22923668 | 0.80 | ALDH1A1 (0.61) | CASP2ALDH1A1CNR1HPGDPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2826493-A1 | Polymer suitable for use in cell culture | Stichting Katholieke Universiteit, Radboud Universiteit Nijmegen (NL) | 2015-01-21 | — | — | EP | disclosed |