Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.60 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17752144 | 0.85 | GBA1 (0.50) | CASP2GBA1NAAATSHRFAAH | |
| SCHEMBL25839499 | 0.82 | L3MBTL1 (0.45) | CASP2GBA1NAAATSHRFAAH | |
| SCHEMBL16405258 | 0.80 | GBA1 (0.47) | CASP2GBA1NAAATSHRFAAH | |
| SCHEMBL14976750 | 0.79 | CASP2 (0.57) | CASP2GBA1NAAAFAAHDNM1 | |
| SCHEMBL7780945 | 0.79 | CASP2 (0.48) | CASP2GBA1NAAATSHRFAAH | |
| SCHEMBL7352291 | 0.79 | CASP2 (0.63) | CASP2NAAAFAAHDNM1LPAR1 | |
| SCHEMBL20048669 | 0.79 | FAAH (0.58) | CASP2NAAAFAAHDNM1LPAR1 | |
| SCHEMBL9324926 | 0.79 | MEN1 (0.52) | CASP2NAAATSHRFAAHMAPT | |
| SCHEMBL8968727 | 0.79 | MEN1 (0.52) | CASP2NAAATSHRFAAHMAPT | |
| SCHEMBL1553172 | 0.79 | CASP2 (0.83) | CASP2NAAAFAAHDNM1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2826493-A1 | Polymer suitable for use in cell culture | Stichting Katholieke Universiteit, Radboud Universiteit Nijmegen (NL) | 2015-01-21 | — | — | EP | disclosed |