SCHEMBL17752188

SCHEMBL17752188

CC(O)(C(=O)OC1C2CC3CC(C2)CC1C3)C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 7/20 0.40
EPHX1 P07099 1/20 0.38
FKBP1A P62942 1/20 0.38
CYP2C9 P11712 1/20 0.36
EPHX2 P34913 2/20 0.35
PDK1 Q15118 1/20 0.33
PDK2 Q15119 1/20 0.33
PDK3 Q15120 1/20 0.33
PDK4 Q16654 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL685897 0.84 HSD11B1 (0.43) HSD11B1EPHX1FKBP1ACYP2C9EPHX2
SCHEMBL17753873 0.82 HSD11B1 (0.42) HSD11B1EPHX1FKBP1ACYP2C9EPHX2
SCHEMBL11337699 0.80 HSD11B1 (0.46) HSD11B1EPHX1FKBP1ACYP2C9EPHX2
SCHEMBL18994289 0.80 HSD11B1 (0.46) HSD11B1EPHX1FKBP1ACYP2C9EPHX2
SCHEMBL12753773 0.79 HSD11B1 (0.39) HSD11B1EPHX1FKBP1ACYP2C9EPHX2
SCHEMBL13194655 0.77 HSD11B1 (0.43) HSD11B1EPHX1FKBP1ACYP2C9EPHX2
SCHEMBL20455834 0.77 HSD11B1 (0.43) HSD11B1EPHX1FKBP1ACYP2C9EPHX2
SCHEMBL24360818 0.74 HSD11B1 (0.41) HSD11B1EPHX1FKBP1ACYP2C9EPHX2
SCHEMBL6722085 0.74 HSD11B1 (0.41) HSD11B1EPHX1FKBP1ACYP2C9EPHX2
SCHEMBL13225276 0.73 HSD11B1 (0.38) HSD11B1EPHX1FKBP1ACYP2C9EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9971241-B2 Compound, resin, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-15 US disclosed
US-20160139508-A1 COMPOUND, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160139508-A1 COMPOUND, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN AFF1, AFF2, AFF4 HSD11B1 563/4885EPHX1 923/4885FKBP1A 3034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.