SCHEMBL17752245

SCHEMBL17752245

O=c1c2ccccc2oc2cc(N3c4ccccc4C4(c5ccccc5-c5ccccc54)c4ccccc43)ccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.46
MAOA P21397 5/20 0.45
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GLA P06280 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
PGAM1 P18669 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
TTR P02766 2/20 0.42
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
NTRK1 P04629 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17752251 0.96 PTGER4 (0.41) PTGER4MAOAHSD17B10KDM4EALDH1A1
SCHEMBL21453612 0.91 PTGER4 (0.47) PTGER4MAOAHSD17B10KDM4EALDH1A1
SCHEMBL17752246 0.91 NPC1 (0.45) PTGER4MAOAHSD17B10KDM4EALDH1A1
SCHEMBL21585316 0.90 PTGER4 (0.39) PTGER4MAOAHSD17B10KDM4EALDH1A1
SCHEMBL17752281 0.89 PTGER4 (0.42) PTGER4MAOAHSD17B10KDM4EALDH1A1
SCHEMBL17752247 0.88 MAOA (0.43) PTGER4MAOAHSD17B10KDM4EALDH1A1
SCHEMBL17752241 0.88 PTGER4 (0.46) PTGER4MAOAHSD17B10KDM4EALDH1A1
SCHEMBL17752249 0.87 MAOA (0.42) PTGER4MAOAHSD17B10KDM4EALDH1A1
SCHEMBL24634214 0.87 MAOA (0.41) PTGER4MAOAHSD17B10KDM4EALDH1A1
SCHEMBL24688788 0.86 MAOA (0.40) PTGER4MAOAHSD17B10KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
EP-3706182-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kyushu University National University Corporation (JP) 2020-09-09 EP disclosed
US-10658596-B2 2020-05-19 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-9685615-B2 Light emitting material, delayed fluorescent emitter, organic light emitting device, and compound KYULUX, INC. (JP) 2017-06-20 US disclosed
US-9685615-B2 Light emitting material, delayed fluorescent emitter, organic light emitting device, and compound KYULUX, INC. (JP) 2017-06-20 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
EP-3171421-A1 ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2017-05-24 EP disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
EP-3035401-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Kyushu University, National University Corporation (JP) 2016-06-22 EP disclosed
US-20160141516-A1 LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT EMITTER, ORGANIC LIGHT EMITTING DEVICE, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-05-19 US disclosed
US-20160141516-A1 LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT EMITTER, ORGANIC LIGHT EMITTING DEVICE, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160141516-A1 LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT EMITTER, ORGANIC LIGHT EMITTING DEVICE, AND COMPOUND CRY2, CRY1, IK PTGER4 2329/4885MAOA 2247/4885HSD17B10 4088/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA PTGER4 2137/4885MAOA 472/4885HSD17B10 936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.