Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17752815 | 1.00 | IDO1 (0.52) | IDO1TP53EGFRUCHL1TAAR1 | |
| SCHEMBL17752820 | 1.00 | IDO1 (0.52) | IDO1TP53EGFRUCHL1TAAR1 | |
| SCHEMBL171069 | 0.92 | IDO1 (0.60) | IDO1TP53TAAR1CYP2A6LPL | |
| SCHEMBL1702558 | 0.86 | TP53 (0.56) | TP53EGFRUCHL1TAAR1HRH3 | |
| SCHEMBL2776957 | 0.86 | TP53 (0.56) | TP53EGFRUCHL1TAAR1HRH3 | |
| SCHEMBL17756332 | 0.86 | IDO1 (0.58) | IDO1TAAR1HRH3 | |
| SCHEMBL441726 | 0.86 | IDO1 (0.58) | IDO1TAAR1HRH3 | |
| SCHEMBL17756329 | 0.86 | IDO1 (0.58) | IDO1TAAR1HRH3 | |
| SCHEMBL17752822 | 0.84 | TP53 (0.47) | IDO1TP53EGFRMETAP2NISCH | |
| SCHEMBL6921140 | 0.79 | NISCH (0.44) | IDO1TP53EGFRUCHL1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137598-A1 | SYNTHESIS OF CYCLOPHANES FROM A SELF-ASSEMBLY REACTION | UNIVERSITY OF OREGON (US) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137598-A1 | SYNTHESIS OF CYCLOPHANES FROM A SELF-ASSEMBLY REACTION | TST, CTH, CBS | IDO1 1121/4885TP53 3881/4885EGFR 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.