Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1776556 | 0.99 | HTR6 (0.63) | HTR6HTR1ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL6427140 | 0.95 | HTR6 (0.59) | HTR6HTR1ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL6463228 | 0.87 | HTR6 (0.60) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL4312550 | 0.83 | HTR6 (0.82) | HTR6HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL4319160 | 0.82 | HTR6 (0.80) | HTR6HTR1ADRD2 | |
| SCHEMBL1775765 | 0.80 | HTR6 (0.61) | HTR6HTR1ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL1774900 | 0.79 | HTR6 (0.60) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL1776123 | 0.79 | HTR6 (0.79) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL1774626 | 0.79 | HTR6 (0.79) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL1775946 | 0.79 | HTR6 (0.69) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |