Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1775865 | 0.99 | HTR6 (0.67) | HTR6EPHX2HSD11B1HTR2C | |
| SCHEMBL1775337 | 0.85 | HTR6 (0.52) | HTR6HSD11B1MEN1KMT2A | |
| SCHEMBL4306547 | 0.82 | HTR6 (0.71) | HTR6MEN1KMT2A | |
| SCHEMBL1776812 | 0.82 | HTR6 (1.00) | HTR6 | |
| Hydrochloric Acid SCHEMBL1774191 | 0.81 | HTR6 (0.98) | HTR6 | |
| SCHEMBL1775359 | 0.79 | HTR6 (0.64) | HTR6 | |
| Hydrochloric Acid SCHEMBL1776556 | 0.78 | HTR6 (0.63) | HTR6 | |
| SCHEMBL1775765 | 0.77 | HTR6 (0.61) | HTR6HTR2C | |
| Hydrochloric Acid SCHEMBL1774900 | 0.76 | HTR6 (0.60) | HTR6HTR2C | |
| Hydrochloric Acid SCHEMBL6463228 | 0.76 | HTR6 (0.60) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |