Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.59 |
| ▸ | ADH1C | P00326 | 2/20 | 0.59 |
| ▸ | ADH1A | P07327 | 2/20 | 0.59 |
| ▸ | ADH7 | P40394 | 2/20 | 0.59 |
| ▸ | ADH4 | P08319 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | CLK3 | P49761 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | PDE8B | O95263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15213162 | 0.88 | — | — | |
| SCHEMBL15213163 | 0.79 | — | — | |
| SCHEMBL1608989 | 0.79 | — | — | |
| SCHEMBL304641 | 0.77 | — | — | |
| SCHEMBL7356997 | 0.76 | NAMPT (0.36) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL2652703 | 0.75 | ADH1B (0.61) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL8952019 | 0.74 | ADH1A (1.00) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL8606031 | 0.74 | ADH1A (1.00) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL5651614 | 0.74 | ADH1A (1.00) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL13243254 | 0.74 | ADH1B (0.74) | ADH1BADH1CADH1AADH7ADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016077375-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-05-19 | — | — | WO | disclosed |