Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 6/20 | 1.00 |
| ▸ | ADH1C | P00326 | 5/20 | 1.00 |
| ▸ | ADH1B | P00325 | 4/20 | 1.00 |
| ▸ | ADH7 | P40394 | 3/20 | 1.00 |
| ▸ | ADH4 | P08319 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303776 | 1.00 | ADH1A (1.00) | ADH1AADH1CADH1BADH7ADH4 | |
| SCHEMBL8606031 | 1.00 | ADH1A (1.00) | ADH1AADH1CADH1BADH7ADH4 | |
| SCHEMBL5651614 | 1.00 | ADH1A (1.00) | ADH1AADH1CADH1BADH7ADH4 | |
| SCHEMBL304641 | 0.97 | — | — | |
| SCHEMBL1608989 | 0.95 | — | — | |
| SCHEMBL207500 | 0.87 | — | — | |
| SCHEMBL23697411 | 0.86 | ADH1B (0.75) | ADH1AADH1CADH1BADH7ADH4 | |
| SCHEMBL13243254 | 0.85 | ADH1B (0.74) | ADH1AADH1CADH1BADH7ADH4 | |
| SCHEMBL24202181 | 0.82 | ADH1B (0.68) | ADH1AADH1CADH1BADH7ADH4 | |
| SCHEMBL24942187 | 0.82 | ADH1B (0.68) | ADH1AADH1CADH1BADH7ADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506239-A | Carbostyril derivative and platelets aggregation inhibitory agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| US-4585774-A | Aniline derivatives and cardiotonic composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0064878-B1 | NOVEL ANILINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CARDIOTONIC COMPOSITIONS CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |