Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17754262 | 0.94 | THRB (0.39) | THRBKMT2AMAPTNFKB1NFKB2 | |
| SCHEMBL17754264 | 0.88 | FFAR1 (0.34) | THRBKMT2AMAPTAKR1C3 | |
| SCHEMBL15582416 | 0.87 | THRB (0.38) | THRBKMT2AMAPTAKR1C3 | |
| SCHEMBL17754254 | 0.87 | AKR1C3 (0.35) | THRBAKR1C3 | |
| SCHEMBL17754252 | 0.86 | FFAR4 (0.35) | THRBKMT2AMAPTAKR1C3 | |
| SCHEMBL15582417 | 0.86 | THRB (0.49) | THRBKMT2AMAPTHPGDLMNA | |
| SCHEMBL17461504 | 0.86 | THRB (0.49) | THRBKMT2AMAPTNFKB1NFKB2 | |
| SCHEMBL17754260 | 0.82 | THRB (0.39) | THRBKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12154226 | 0.82 | THRB (0.52) | THRBKMT2AMAPTHPGDLMNA | |
| SCHEMBL17340246 | 0.82 | THRB (0.62) | THRBKMT2AMAPTNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137921-A1 | POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME | DIC CORPORATION (JP) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137921-A1 | POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME | RCC1, LPXN, SMC4 | THRB 4879/4885KMT2A 2308/4885MAPT 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.