Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1207026 | 0.81 | POLB (0.57) | LMNAALDH1A1L3MBTL1HPGDKMT2A | |
| SCHEMBL30040417 | 0.81 | POLB (0.57) | LMNAALDH1A1L3MBTL1HPGDKMT2A | |
| SCHEMBL17754986 | 0.80 | HTT (0.51) | LMNAALDH1A1L3MBTL1HPGDKMT2A | |
| SCHEMBL17755051 | 0.79 | KMT2A (0.57) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL17755173 | 0.78 | NOTUM (0.62) | LMNAALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL5907668 | 0.77 | HPGD (0.67) | LMNAALDH1A1HPGDHDAC3HDAC4 | |
| SCHEMBL14826375 | 0.77 | LMNA (0.73) | LMNAALDH1A1L3MBTL1HPGDKMT2A | |
| SCHEMBL17755257 | 0.76 | POLB (0.51) | LMNAL3MBTL1HPGDKMT2ANPSR1 | |
| SCHEMBL28652196 | 0.76 | HPGD (0.61) | LMNAALDH1A1HPGDHDAC3HDAC4 | |
| SCHEMBL27602952 | 0.76 | L3MBTL1 (0.51) | LMNAALDH1A1L3MBTL1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040049-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO, LLC (US) | 2021-02-11 | — | — | US | disclosed |
| US-10723708-B2 | Anti-HCMV compositions and methods | EVRYS BIO, LLC (US) | 2020-07-28 | — | — | US | disclosed |
| US-20180170884-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | FORGE LIFE SCIENCE, LLC | 2018-06-21 | — | — | US | disclosed |
| US-20180170884-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | FORGE LIFE SCIENCE, LLC | 2018-06-21 | — | — | US | disclosed |
| WO-2016077240-A2 | ANTI-HCMV COMPOSITIONS AND METHODS | FORGE LIFE SCIENCE, LLC (US) | 2016-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10723708-B2 | Anti-HCMV compositions and methods | RPL35, RPL7, RPL5 | LMNA 1477/4885ALDH1A1 3921/4885L3MBTL1 2803/4885 |
| US-20210040049-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | RPL35, RPL7, RPL5 | LMNA 1477/4885ALDH1A1 3921/4885L3MBTL1 2803/4885 |
| US-20180170884-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | RPL35, RPL7, RPL5 | LMNA 1477/4885ALDH1A1 3921/4885L3MBTL1 2803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.