SCHEMBL17755324

SCHEMBL17755324

CC(COS(C)(=O)=O)c1ccccc1Br

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
PLCG1 P19174 1/20 0.38
CYP2C19 P33261 2/20 0.37
CYP2C9 P11712 1/20 0.37
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
POLB P06746 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17749157 0.80 CASP1 (0.39) ALDH1A1CYP3A4L3MBTL1IDO1TDO2
SCHEMBL31626942 0.79 KDM4E (0.42) HTTPLCG1CYP2C19CYP2C9ALDH1A1
SCHEMBL7255639 0.75 TAAR1 (0.45)
SCHEMBL7255641 0.75 TAAR1 (0.45)
SCHEMBL7259968 0.75 TAAR1 (0.45)
SCHEMBL5878353 0.72 PLCG1 (0.38) PLCG1ALDH1A1POLB
SCHEMBL15923854 0.72 CA1 (0.42) HTTPLCG1CYP2C19CYP2C9MAOA
SCHEMBL5877993 0.72 PLCG1 (0.38) PLCG1ALDH1A1POLB
SCHEMBL5877986 0.72 PLCG1 (0.38) PLCG1ALDH1A1POLB
SCHEMBL2529599 0.72 LMNA (0.52) HTTCYP2C19CYP2C9ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180170884-A1 ANTI-HCMV COMPOSITIONS AND METHODS FORGE LIFE SCIENCE, LLC 2018-06-21 US disclosed
WO-2016077240-A2 ANTI-HCMV COMPOSITIONS AND METHODS FORGE LIFE SCIENCE, LLC (US) 2016-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180170884-A1 ANTI-HCMV COMPOSITIONS AND METHODS RPL35, RPL7, RPL5 HTT 3200/4885PLCG1 1250/4885CYP2C19 4784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.