SCHEMBL1775569

SCHEMBL1775569

NCCCCCC(=O)N1CCNCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 6/20 0.49
GNAI1 P63096 6/20 0.49
GNAO1 P09471 5/20 0.49
ALDH1A1 P00352 2/20 0.47
ITGB3 P05106 4/20 0.45
ITGA2B P08514 4/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.43
RAD52 P43351 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
PLG P00747 1/20 0.42
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42
ALOX15 P16050 1/20 0.42
SLC6A2 P23975 1/20 0.42
RECQL P46063 1/20 0.42
SLC6A3 Q01959 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PAOX Q6QHF9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1931088 0.98 GNAI3 (0.51) GNAI3GNAI1GNAO1ALDH1A1ITGB3
Hydrochloric Acid SCHEMBL1930351 0.98 GNAI3 (0.51) GNAI3GNAI1GNAO1ALDH1A1ITGB3
SCHEMBL23471162 0.98 ALDH1A1 (0.48) GNAI3GNAI1GNAO1ALDH1A1ITGB3
SCHEMBL30734427 0.92 ATM (0.48) GNAI3GNAI1GNAO1ALDH1A1ITGB3
SCHEMBL14540476 0.91 ATM (0.46) GNAI3GNAI1GNAO1ALDH1A1ITGB3
SCHEMBL9415827 0.90 GNAI3 (0.56) GNAI3GNAI1GNAO1ITGB3ITGA2B
SCHEMBL16756662 0.90 GNAI3 (0.56) GNAI3GNAI1GNAO1ITGB3ITGA2B
SCHEMBL10337915 0.90 GNAI3 (0.56) GNAI3GNAI1GNAO1ITGB3ITGA2B
SCHEMBL9415769 0.90 GNAI3 (0.56) GNAI3GNAI1GNAO1ITGB3ITGA2B
SCHEMBL829119 0.89 SIGMAR1 (0.50) GNAI3GNAI1GNAO1ALDH1A1ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2024499-B1 OLIGONUCLEOTIDE ANALOGS HAVING CATIONIC INTERSUBUNIT LINKAGES SAREPTA THERAPEUTICS INC (US) 2017-10-25 EP disclosed
EP-2735568-B1 Oligonucleotide analogs having cationic intersubunit linkages AVI BIOPHARMA INC (US) 2017-08-02 EP disclosed
EP-2735568-A1 Oligonucleotide analogs having cationic intersubunit linkages AVI BioPharma, Inc. (US) 2014-05-28 EP disclosed
US-7943762-B2 Oligonucleotide analogs having cationic intersubunit linkages AVI BIOPHARMA, INC. (US) 2011-05-17 US disclosed
US-20090088562-A1 Oligonucleotide analogs having cationic intersubunit linkages JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2009-04-02 US disclosed
EP-2024499-A2 OLIGONUCLEOTIDE ANALOGS HAVING CATIONIC INTERSUBUNIT LINKAGES Avi Biopharma, Inc. (US) 2009-02-18 EP disclosed
WO-2008036127-A2 OLIGONUCLEOTIDE ANALOGS HAVING CATIONIC INTERSUBUNIT LINKAGES AVI BIOPHARMA, INC. (US) 2008-03-27 WO disclosed
WO-2007096137-A1 AMPHOTERICIN DERIVATIVES ETH ZURICH (CH) 2007-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088562-A1 Oligonucleotide analogs having cationic intersubunit linkages SLC38A7, SLC43A3, SLC28A3 GNAI3 3213/4885GNAI1 3504/4885GNAO1 2293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.