Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.59 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516240 | 0.91 | NPSR1 (0.56) | SMYD3MGAMGAASIMGAM2 | |
| SCHEMBL6237922 | 0.88 | GNAI3 (0.53) | SMYD3MGAMGAASIMGAM2 | |
| SCHEMBL7018511 | 0.81 | SMYD3 (0.43) | SMYD3MGAMGAASIMGAM2 | |
| SCHEMBL26660463 | 0.81 | NPSR1 (0.52) | SMYD3MGAMGAASIMGAM2 | |
| SCHEMBL10466951 | 0.81 | GAA (0.50) | SMYD3MGAMGAASIMGAM2 | |
| Hydrochloric Acid SCHEMBL10468165 | 0.79 | GAA (0.48) | SMYD3MGAMGAASIMGAM2 | |
| SCHEMBL23084195 | 0.78 | SMYD3 (0.50) | SMYD3MGAMGAASIMGAM2 | |
| SCHEMBL7788916 | 0.77 | SMYD3 (0.47) | SMYD3MGAMGAASIMGAM2 | |
| SCHEMBL18380884 | 0.77 | SMYD3 (0.47) | SMYD3MGAMGAASIMGAM2 | |
| SCHEMBL7470486 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018178008-A1 | SUBSTITUTED ISOXAZOLINE-5-ONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-04 | — | — | WO | disclosed |
| WO-2018177836-A1 | N-CYCLOPROPYL-2-OXOPYRROLIDINE-3-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HERBICIDAL PLANT PROTECTION AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-04 | — | — | WO | disclosed |
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | CYP3A7, CYP2C19, CYP3A5 | SMYD3 3066/4885MGAM 537/4885GAA 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.