SCHEMBL17756705

SCHEMBL17756705

CCOC(=O)C(C)(C)CCCCCOCCCCCC(C)(C)C(C)=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.63
CYP4A11 Q02928 3/20 0.63
HTT P42858 1/20 0.45
PKM P14618 2/20 0.42
THRB P10828 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CES2 O00748 2/20 0.36
TBXAS1 P24557 1/20 0.36
KDM4E B2RXH2 1/20 0.33
ELANE P08246 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PRKCA P17252 1/20 0.32
ACLY P53396 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17756704 1.00 CYP4F2 (0.63) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL17756696 0.98 CYP4F2 (0.60) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL17756706 0.97 CYP4F2 (0.58) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL17746745 0.93 CYP4F2 (0.71) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL17746731 0.93 CYP4F2 (0.71) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL20371022 0.92 CYP4F2 (0.69) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL3040974 0.92 CYP4F2 (0.68) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL17746737 0.90 CYP4F2 (0.66) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL22016457 0.89 CYP4F2 (0.65) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL6253618 0.87 CYP4F2 (0.63) CYP4F2CYP4A11HTTPKMTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180194713-A1 PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS GEMPHIRE THERAPEUTICS INC. 2018-07-12 US disclosed
US-20170158601-A9 PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS GEMPHIRE THERAPEUTICS INC. 2017-06-08 US disclosed
US-20160137584-A1 PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS GEMPHIRE THERAPEUTICS INC. 2016-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194713-A1 PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS DGKI, DGKA, SQLE CYP4F2 129/4885CYP4A11 250/4885HTT 3934/4885
US-20160137584-A1 PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS BCKDK, DGKI, DDC CYP4F2 87/4885CYP4A11 155/4885HTT 3221/4885
US-20170158601-A9 PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS BCKDK, DGKI, DDC CYP4F2 87/4885CYP4A11 155/4885HTT 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.