Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758747 | 0.85 | NOTUM (0.51) | LMNAMPONOTUMALDH1A1MAPT | |
| SCHEMBL20929496 | 0.85 | NOTUM (0.38) | LMNAMPOGLSPI4KBNOTUM | |
| SCHEMBL17758820 | 0.80 | LMNA (0.46) | LMNAMPOGLSPI4KBALDH1A1 | |
| SCHEMBL20929259 | 0.80 | POLB (0.35) | LMNAPI4KBNOTUMALDH1A1MAPT | |
| SCHEMBL17758811 | 0.79 | SMN1; SMN2 (0.49) | LMNAMPOGLSALDH1A1MAPT | |
| SCHEMBL23352194 | 0.78 | LMNA (0.44) | LMNANOTUMALDH1A1MAPTKLKB1 | |
| SCHEMBL17758803 | 0.77 | MAPT (0.41) | LMNAMPOGLSPI4KBALDH1A1 | |
| SCHEMBL20929575 | 0.76 | HCRTR1 (0.40) | ALDH1A1MAPTHCRTR1HCRTR2KMT2A | |
| SCHEMBL23352235 | 0.76 | MAPT (0.38) | ALDH1A1MAPTHCRTR1HCRTR2KMT2A | |
| SCHEMBL17758815 | 0.76 | LMNA (0.44) | LMNAMPOGLSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459321-B2 | Broad spectrum antiviral compositions and methods | EVRYS BIO, LLC (US) | 2022-10-04 | — | — | US | disclosed |
| US-11358961-B2 | Anti-HCMV compositions and methods | EVRYS BIO, LLC (US) | 2022-06-14 | — | — | US | disclosed |
| US-20220135556-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO, LLC (US) | 2022-05-05 | — | — | US | disclosed |
| US-20210139475-A1 | Broad Spectrum Antiviral Compositions and Methods | EVRYS BIO, LLC (US) | 2021-05-13 | — | — | US | disclosed |
| EP-3218373-B1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO LLC (US) | 2020-07-22 | — | — | EP | disclosed |
| US-20200140429-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO, LLC (US) | 2020-05-07 | — | — | US | disclosed |
| US-10556894-B2 | Anti-HCMV compositions and methods | EVRYS BIO, LLC (US) | 2020-02-11 | — | — | US | disclosed |
| WO-2019079519-A1 | BROAD SPECTRUM ANTIVIRAL COMPOSITIONS AND METHODS | FORGE LIFE SCIENCE, LLC (US) | 2019-04-25 | — | — | WO | disclosed |
| WO-2016077232-A2 | ANTI-HCMV COMPOSITIONS AND METHODS | FORGE LIFE SCIENCE, LLC (US) | 2016-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11459321-B2 | Broad spectrum antiviral compositions and methods | IRF3, MAVS, ZC3HAV1 | LMNA 2718/4885MPO 3412/4885GLS 1655/4885 |
| US-11358961-B2 | Anti-HCMV compositions and methods | RPL35, RPL7, RPL5 | LMNA 1720/4885MPO 2075/4885GLS 2041/4885 |
| US-10556894-B2 | Anti-HCMV compositions and methods | RPL35, RPL7, RPL5 | LMNA 1720/4885MPO 2075/4885GLS 2041/4885 |
| US-20210139475-A1 | Broad Spectrum Antiviral Compositions and Methods | MAVS, IRF3, ZC3HAV1 | LMNA 3185/4885MPO 3066/4885GLS 1455/4885 |
| US-20200140429-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | RPL35, RPL7, RPL5 | LMNA 1720/4885MPO 2075/4885GLS 2041/4885 |
| US-20220135556-A1 | ANTI-HCMV COMPOSITIONS AND METHODS | RPL35, RPL7, RPL5 | LMNA 1720/4885MPO 2075/4885GLS 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.