SCHEMBL17758807

SCHEMBL17758807

CC(=O)c1ccc(-c2ncccn2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HSD17B1 P14061 1/20 0.54
RAB9A P51151 2/20 0.50
CLK4 Q9HAZ1 2/20 0.50
XDH P47989 1/20 0.50
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 2/20 0.47
MAOB P27338 1/20 0.46
ADRB2 P07550 1/20 0.45
HPGD P15428 3/20 0.45
LMNA P02545 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
KMT2A Q03164 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
BRD4 O60885 1/20 0.44
AURKA O14965 1/20 0.44
MAP4K4 O95819 1/20 0.44
PAK4 O96013 1/20 0.44
ABL1 P00519 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20253314 0.98 MAPT (0.63) MAPTSMN1; SMN2HSD17B1RAB9ACLK4
SCHEMBL30447126 0.80 MAPT (0.57) MAPTSMN1; SMN2ALDH1A1MAOBABL1
SCHEMBL933588 0.80 MAPT (0.57) MAPTSMN1; SMN2ALDH1A1MAOBABL1
SCHEMBL1222172 0.80 MKNK1 (0.55) RAB9ACLK4NPC1ALDH1A1
SCHEMBL23691953 0.79 MAPT (0.60) MAPTSMN1; SMN2HSD17B1RAB9AXDH
SCHEMBL8365593 0.79 MEN1 (0.47) MAPTSMN1; SMN2HSD17B1RAB9AXDH
SCHEMBL13617393 0.78 MKNK1 (0.62) MAPTSMN1; SMN2RAB9ANPC1ALDH1A1
SCHEMBL3553363 0.78 CLK4 (0.45) RAB9ACLK4NPC1ALDH1A1MAOB
SCHEMBL197130 0.78 MAPT (0.80) MAPTSMN1; SMN2HSD17B1RAB9AXDH
SCHEMBL11441494 0.78 MAPT (0.80) MAPTSMN1; SMN2HSD17B1RAB9AXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11358961-B2 Anti-HCMV compositions and methods EVRYS BIO, LLC (US) 2022-06-14 US disclosed
US-20220135556-A1 ANTI-HCMV COMPOSITIONS AND METHODS EVRYS BIO, LLC (US) 2022-05-05 US disclosed
EP-3218373-B1 ANTI-HCMV COMPOSITIONS AND METHODS EVRYS BIO LLC (US) 2020-07-22 EP disclosed
US-20200140429-A1 ANTI-HCMV COMPOSITIONS AND METHODS EVRYS BIO, LLC (US) 2020-05-07 US disclosed
US-10556894-B2 Anti-HCMV compositions and methods EVRYS BIO, LLC (US) 2020-02-11 US disclosed
WO-2018105776-A1 PHENANTHROLINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING SAME 주식회사 진웅산업 2018-06-14 WO disclosed
WO-2016077232-A2 ANTI-HCMV COMPOSITIONS AND METHODS FORGE LIFE SCIENCE, LLC (US) 2016-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11358961-B2 Anti-HCMV compositions and methods RPL35, RPL7, RPL5 MAPT 1391/4885SMN1; SMN2 3438/4885HSD17B1 2444/4885
US-10556894-B2 Anti-HCMV compositions and methods RPL35, RPL7, RPL5 MAPT 1391/4885SMN1; SMN2 3438/4885HSD17B1 2444/4885
US-20200140429-A1 ANTI-HCMV COMPOSITIONS AND METHODS RPL35, RPL7, RPL5 MAPT 1391/4885SMN1; SMN2 3438/4885HSD17B1 2444/4885
US-20220135556-A1 ANTI-HCMV COMPOSITIONS AND METHODS RPL35, RPL7, RPL5 MAPT 1391/4885SMN1; SMN2 3438/4885HSD17B1 2444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.