Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 3/20 | 0.54 |
| ▸ | BCR | P11274 | 3/20 | 0.54 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30447126 | 1.00 | MAPT (0.57) | MAPTSMN1; SMN2TRPV1ABL1BCR | |
| SCHEMBL16581273 | 0.85 | MAP4K4 (0.54) | MAPTSMN1; SMN2ABL1BCRCHEK2 | |
| SCHEMBL27605053 | 0.85 | SLC6A7 (0.55) | MAPTTRPV1ABL1BCRSLC6A7 | |
| SCHEMBL30937997 | 0.84 | MAP4K4 (0.55) | SMN1; SMN2ABL1ALDH1A1CHEK2 | |
| SCHEMBL17742695 | 0.84 | MAP4K4 (0.55) | SMN1; SMN2ABL1ALDH1A1CHEK2 | |
| SCHEMBL22282152 | 0.84 | KDM4E (0.49) | ABL1ALDH1A1CYP1A2 | |
| SCHEMBL24475730 | 0.83 | MEN1 (0.55) | MAPTSMN1; SMN2ALDH1A1DHODHCYP2C19 | |
| SCHEMBL2459153 | 0.83 | SLC6A7 (0.54) | TRPV1ABL1BCRSLC6A7CHEK2 | |
| SCHEMBL5858 | 0.83 | KDM4E (0.61) | TRPV1SLC6A7DHODH | |
| SCHEMBL29788328 | 0.83 | KDM4E (0.61) | TRPV1SLC6A7DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11092452-A | — | — | None | — | — | JP | disclosed |
| EP-3528813-B1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ABS DEV 1 INC (US) | 2025-04-16 | — | — | EP | disclosed |
| US-20240391925-A1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ASANA BIOSCIENCES, LLC (US) | 2024-11-28 | — | — | US | disclosed |
| US-12077543-B2 | P2X3 and/or P2X2/3 compounds and methods | ASANA BIOSCIENCES, LLC (US) | 2024-09-03 | — | — | US | disclosed |
| US-11999720-B2 | Pyrazolylacylpyrazoline compounds and method for treating pain | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2024-06-04 | — | — | US | disclosed |
| CN-116854693-A | P2X 3 And/or P2X 2/3 Compounds and methods | 阿沙纳生物科学公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-109996546-B | P2X 3 And/or P2X 2/3 Compounds and methods | 阿沙纳生物科学公司 | 2023-06-27 | — | — | CN | disclosed |
| US-20230125122-A1 | NOVEL TRANSITION METAL ELECTRON TRANSFER COMPLEX HAVING C-N LIGAND AND ELECTROCHEMICAL BIO SENSOR USING SAME | SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION (KR) | 2023-04-27 | — | — | US | disclosed |
| US-20220227774-A1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ASANA BIOSCIENCES, LLC | 2022-07-21 | — | — | US | disclosed |
| US-11339169-B2 | P2X3 and/or P2X2/3 compounds and methods | ASANA BIOSCIENCES, LLC (US) | 2022-05-24 | — | — | US | disclosed |
| EP-1697431-A1 | BORON-CONTAINING POLYMER COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | disclosed |
| WO-2005061562-A1 | BORON-CONTAINING POLYMER COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | SHOWA DENKO K.K. (JP) | 2005-07-07 | — | — | WO | disclosed |
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| CN-1056840-C | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2000-09-27 | — | — | CN | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| CN-1219927-A | Phenylalkylcarboxylic acid derivatives | SANKYO CO (JP) | 1999-06-16 | — | — | CN | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |
| JP-H1192452-A | PRODUCTION OF 4'-(2-PYRIDYL)ACETOPHENONE | SANKYO CO LTD | 1999-04-06 | — | — | JP | disclosed |
| CN-1143639-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1997-02-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227774-A1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | P2RX3, P2RX6, P2RX2 | MAPT 4820/4885SMN1; SMN2 487/4885TRPV1 26/4885 |
| US-11339169-B2 | P2X3 and/or P2X2/3 compounds and methods | P2RX3, P2RX6, P2RX2 | MAPT 4820/4885SMN1; SMN2 487/4885TRPV1 26/4885 |
| US-12077543-B2 | P2X3 and/or P2X2/3 compounds and methods | P2RX3, P2RX6, P2RX2 | MAPT 4820/4885SMN1; SMN2 487/4885TRPV1 26/4885 |
| US-20230125122-A1 | NOVEL TRANSITION METAL ELECTRON TRANSFER COMPLEX HAVING C-N LIGAND AND ELECTROCHEMICAL BIO SENSOR USING SAME | MB, CACYBP, SPR | MAPT 3579/4885SMN1; SMN2 4798/4885TRPV1 2249/4885 |
| US-20240391925-A1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | P2RX3, P2RX6, P2RX2 | MAPT 4820/4885SMN1; SMN2 487/4885TRPV1 26/4885 |
| US-11999720-B2 | Pyrazolylacylpyrazoline compounds and method for treating pain | ACHE, TRPV1, GRIK3 | MAPT 388/4885SMN1; SMN2 248/4885TRPV1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.