SCHEMBL197130

SCHEMBL197130

CC(=O)c1ccc(-c2ccc(C(C)=O)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.80
HSD17B1 P14061 3/20 0.80
SMN1; SMN2 Q16637 2/20 0.80
HPGD P15428 3/20 0.59
LMNA P02545 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
RAB9A P51151 2/20 0.59
KMT2A Q03164 1/20 0.59
XDH P47989 1/20 0.57
KIF11 P52732 1/20 0.53
MAPK1 P28482 2/20 0.52
NOS3 P29474 2/20 0.52
NOS1 P29475 2/20 0.52
ALDH1A1 P00352 1/20 0.50
BRD4 O60885 1/20 0.50
NPC1 O15118 1/20 0.50
STAT3 P40763 1/20 0.50
STAT1 P42224 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MMP2 P08253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11441494 1.00 MAPT (0.80) MAPTHSD17B1SMN1; SMN2HPGDLMNA
Water SCHEMBL9631932 0.97 HSD17B1 (0.76) MAPTHSD17B1SMN1; SMN2HPGDLMNA
SCHEMBL11754087 0.92 HSD17B1 (0.70) MAPTHSD17B1SMN1; SMN2HPGDLMNA
SCHEMBL50646 0.90 MAPT (0.68) MAPTHSD17B1SMN1; SMN2HPGDLMNA
SCHEMBL15960261 0.89 SMN1; SMN2 (0.74) MAPTHSD17B1SMN1; SMN2HPGDLMNA
SCHEMBL1271569 0.89 SMN1; SMN2 (0.67) MAPTHSD17B1SMN1; SMN2HPGDLMNA
SCHEMBL7252924 0.89 MAPT (1.00) MAPTHSD17B1SMN1; SMN2HPGDLMNA
SCHEMBL7738989 0.89 MAPT (1.00) MAPTHSD17B1SMN1; SMN2HPGDLMNA
SCHEMBL4085842 0.89 HSD17B1 (1.00) MAPTHSD17B1SMN1; SMN2HPGDLMNA
SCHEMBL19730946 0.89 MAPT (0.67) MAPTHSD17B1SMN1; SMN2HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119570564-A Thermosensitive microcapsule essence for steam eyeshade and preparation method thereof 浙江珍视明眼健康产业有限公司 2025-03-07 CN claimed
CN-115340517-B Polarity-sensitive cationic fluorescent dye and preparation method and application thereof 云南大学 2023-06-20 CN claimed
CN-114957685-B Pyridyl-containing covalent organic framework material and preparation method and application thereof 东南大学 2023-04-21 CN claimed
CN-111589472-B Carboxyl-containing conjugated microporous polymer/TiO 2 Method for preparing composite material 齐齐哈尔大学 2022-11-29 CN claimed
CN-115340517-A Polar sensitive cationic fluorescent dye and preparation method and application thereof 云南大学 2022-11-15 CN claimed
CN-114957685-A Covalent organic framework material containing pyridyl and preparation method and application thereof 东南大学 2022-08-30 CN claimed
CN-114181046-A Preparation method of 4,4' -biphenol with low energy consumption 宁夏清研高分子新材料有限公司 2022-03-15 CN claimed
CN-112957928-B Microporous polymer composite membrane and preparation method thereof 北京工商大学 2022-02-22 CN claimed
CN-112957928-A Microporous polymer composite membrane and preparation method thereof 北京工商大学 2021-06-15 CN claimed
CN-112920382-A In-situ method for preparing conjugated microporous polymer TiO2Method for compounding nano antibacterial agent 齐齐哈尔大学 2021-06-08 CN claimed
WO-2016113761-A1 HYDROPHOBIC POLYMER-SUPPORTED LEWIS ACID CATALYST AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-07-21 WO claimed
EP-1337229-B1 IMMOBILISATION OF ACTIVE AGENTS ON FIBRES HENKEL AG & CO KGAA (DE) 2009-09-30 EP claimed
EP-1337229-A2 IMMOBILISATION OF ACTIVE AGENTS ON FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2003-08-27 EP claimed
WO-2002043675-A2 IMMOBILISATION OF ACTIVE AGENTS ON FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-06-06 WO claimed
EP-0465738-A2 Process for producing tetraepoxy resins, epoxy resin compositions, tetraepoxy resins and tetrahydric phenol compounds DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-01-15 EP claimed
US-5041666-A Acetylating biphenyl, oximating, double Beckmann rearrangement, nitrating, hydrolysis, and reducing HOECHST CELANESE CORPORATION (US) 1991-08-20 US claimed
EP-0308841-A2 Process for the preparation of 4,4'-dihydroxybiphenyl BASF Aktiengesellschaft (DE) 1989-03-29 EP claimed
US-4762909-A Method for making polyketones THE DOW CHEMICAL COMPANY (US) 1988-08-09 US claimed
US-4000187-A THERMAL STABILITY, COATINGS, CAST FILMS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1976-12-28 US claimed
US-3970579-A Low melting liquid-crystal mixtures OWENS-ILLINOIS, INC. (US) 1976-07-20 US claimed