Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CALML3 | P27482 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SDHA | P31040 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17760457 | 0.87 | MAOA (0.41) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL17760208 | 0.87 | MAOA (0.41) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393295 | 0.86 | MAOA (0.60) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL17760069 | 0.85 | MAOA (0.41) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL17760465 | 0.83 | MAOA (0.41) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL17760212 | 0.81 | MAOA (0.40) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL17760912 | 0.80 | RAB9A (0.46) | MAOALMNAF10 | |
| SCHEMBL1394034 | 0.79 | MAOA (0.55) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL22261648 | 0.79 | MAOA (0.40) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL17760184 | 0.78 | MAOA (0.38) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016077818-A1 | METHOD FOR TREATING, PREVENTING, OR REDUCING THE RISK OF SKIN INFECTION | MELINTA THERAPEUTICS, INC. (US) | 2016-05-19 | — | — | WO | disclosed |