Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | CCR3 | P51677 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830169 | 1.00 | ACHE (0.67) | ACHESIGMAR1CCR3DRD2DRD4 | |
| SCHEMBL17495605 | 1.00 | ACHE (0.67) | ACHESIGMAR1CCR3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL28538225 | 0.98 | ACHE (0.65) | ACHESIGMAR1CCR3DRD2DRD4 | |
| Cadaverine Tartrate SCHEMBL31269600 | 0.88 | ACHE (0.52) | ACHESIGMAR1DRD4BCHEMEN1 | |
| SCHEMBL1826258 | 0.85 | SIGMAR1 (0.58) | ACHESIGMAR1MC4RBACE1BCHE | |
| SCHEMBL1307820 | 0.85 | SIGMAR1 (0.58) | ACHESIGMAR1MC4RBACE1BCHE | |
| SCHEMBL1471041 | 0.85 | SIGMAR1 (0.58) | ACHESIGMAR1MC4RBACE1BCHE | |
| Hydrochloric Acid SCHEMBL18788467 | 0.83 | SIGMAR1 (0.56) | ACHESIGMAR1MC4RBACE1BCHE | |
| SCHEMBL10720875 | 0.83 | ACHE (0.57) | ACHESIGMAR1CCR3DRD2DRD4 | |
| Ammonia Solution, Strong SCHEMBL2945383 | 0.82 | ACHE (0.96) | ACHESIGMAR1CCR3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688773-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT | Biophore India Pharmaceuticals Pvt. Ltd. (IN) | 2026-02-11 | — | — | EP | claimed |
| CN-119264064-A | Synthetic method of high chiral purity suvorexant intermediate | 安徽联创生物医药股份有限公司 | 2025-01-07 | — | — | CN | claimed |
| WO-2024201424-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD (IN) | 2024-10-03 | — | — | WO | claimed |
| EP-4688773-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT | Biophore India Pharmaceuticals Pvt. Ltd. (IN) | 2026-02-11 | — | — | EP | disclosed |
| CN-119264064-A | Synthetic method of high chiral purity suvorexant intermediate | 安徽联创生物医药股份有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-119264064-A | Synthetic method of high chiral purity suvorexant intermediate | 安徽联创生物医药股份有限公司 | 2025-01-07 | — | — | CN | disclosed |
| WO-2024201424-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD (IN) | 2024-10-03 | — | — | WO | disclosed |
| EP-3412665-B1 | SUVOREXANT INTERMEDIATES AND PREPARATION METHODS THEREOF | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2021-03-03 | — | — | EP | disclosed |
| US-10618891-B2 | Suvorexant intermediate and preparation method thereof | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. (CN) | 2020-04-14 | — | — | US | disclosed |
| US-20190040052-A1 | SUVOREXANT INTERMEDIATE AND PREPARATION METHOD THEREOF | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. (CN) | 2019-02-07 | — | — | US | disclosed |
| WO-2017133620-A1 | SUVOREXANT INTERMEDIATE AND PREPARATION METHOD THEREOF | 浙江华海药业股份有限公司 | 2017-08-10 | — | — | WO | disclosed |
| US-20160168138-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT | REDDY S LAB LIMTED DR (IN) | 2016-06-16 | — | — | US | disclosed |
| US-20160168138-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT | REDDY S LAB LIMTED DR (IN) | 2016-06-16 | — | — | US | disclosed |
| US-20160168138-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT | REDDY S LAB LIMTED DR (IN) | 2016-06-16 | — | — | US | disclosed |
| EP-3021851-A2 | PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT | Dr. Reddy's Laboratories Ltd. (IN) | 2016-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040052-A1 | SUVOREXANT INTERMEDIATE AND PREPARATION METHOD THEREOF | COMT, KMO, CYP4B1 | ACHE 1574/4885SIGMAR1 271/4885CCR3 2997/4885 |
| US-10618891-B2 | Suvorexant intermediate and preparation method thereof | COMT, KMO, CYP4B1 | ACHE 1574/4885SIGMAR1 271/4885CCR3 2997/4885 |
| US-20160168138-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT | KMO, HCRTR2, COMT | ACHE 2288/4885SIGMAR1 284/4885CCR3 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.