Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17765432 | 0.89 | KMT2A (0.40) | ALDH1A1NPC1MEN1CYP1A2CYP3A4 | |
| SCHEMBL17765434 | 0.87 | ALDH1A1 (0.46) | ALDH1A1NPC1MEN1CYP1A2CYP3A4 | |
| SCHEMBL17765460 | 0.85 | ALDH1A1 (0.44) | ALDH1A1NPC1MEN1CYP1A2CYP3A4 | |
| SCHEMBL17765453 | 0.79 | NPC1 (0.37) | ALDH1A1NPC1MEN1CYP1A2CYP3A4 | |
| SCHEMBL6535646 | 0.75 | NPC1 (0.50) | ALDH1A1NPC1MEN1CYP1A2CYP3A4 | |
| SCHEMBL17773364 | 0.72 | NPC1 (0.38) | ALDH1A1NPC1MEN1CYP1A2CYP3A4 | |
| SCHEMBL28282150 | 0.71 | NPC1 (0.50) | ALDH1A1NPC1MEN1CYP1A2CYP3A4 | |
| SCHEMBL2799259 | 0.71 | CACNA2D1 (0.56) | ALDH1A1MEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17765465 | 0.71 | FFAR1 (0.39) | ALDH1A1NPC1MEN1CYP1A2CYP3A4 | |
| SCHEMBL17765416 | 0.71 | KDM4E (0.35) | ALDH1A1NPC1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676679-B2 | Traceless directing groups in radical cascades: from oligoalkynes to fused helicenes without tethered initators | The Florida State University Research Foundation, Inc. (US) | 2017-06-13 | — | — | US | disclosed |
| US-9676679-B2 | Traceless directing groups in radical cascades: from oligoalkynes to fused helicenes without tethered initators | The Florida State University Research Foundation, Inc. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160145276-A1 | TRACELESS DIRECTING GROUPS IN RADICAL CASCADES: FROM OLIGOALKYNES TO FUSED HELICENES WITHOUT TETHERED INITATORS | The Florida State University Research Foundation, Inc | 2016-05-26 | — | — | US | disclosed |
| US-20160145276-A1 | TRACELESS DIRECTING GROUPS IN RADICAL CASCADES: FROM OLIGOALKYNES TO FUSED HELICENES WITHOUT TETHERED INITATORS | The Florida State University Research Foundation, Inc | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145276-A1 | TRACELESS DIRECTING GROUPS IN RADICAL CASCADES: FROM OLIGOALKYNES TO FUSED HELICENES WITHOUT TETHERED INITATORS | OR51E2, OR10J3, ORC3 | ALDH1A1 1301/4885NPC1 2671/4885MEN1 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.