Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.56 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14677386 | 0.82 | CACNA2D1 (0.39) | CACNA2D1CACNB2CACNA1CALDH1A1KDM4E | |
| SCHEMBL2800138 | 0.80 | ALOX5 (0.40) | CACNA2D1CACNB2CACNA1CALDH1A1LMNA | |
| SCHEMBL11363920 | 0.80 | CACNA2D1 (0.49) | CACNA2D1CACNB2CACNA1CTSHRALDH1A1 | |
| SCHEMBL2198244 | 0.80 | SMN1; SMN2 (0.49) | CACNA2D1CACNB2CACNA1CTSHRLMNA | |
| SCHEMBL9547891 | 0.79 | TSHR (0.64) | CACNA2D1CACNB2CACNA1CTSHRALDH1A1 | |
| SCHEMBL28686702 | 0.78 | CACNA2D1 (0.38) | CACNA2D1CACNB2CACNA1CTSHRALDH1A1 | |
| SCHEMBL2801028 | 0.78 | CES2 (0.41) | CACNA2D1CACNB2CACNA1C | |
| SCHEMBL9130467 | 0.77 | ALDH1A1 (0.40) | CACNA2D1CACNB2CACNA1CTSHRALDH1A1 | |
| SCHEMBL2197891 | 0.77 | ALOX5 (0.46) | CACNA2D1CACNB2CACNA1CKDM4E | |
| SCHEMBL2803495 | 0.76 | AOC3 (0.47) | TSHRMAPK1CHRM2PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117976988-A | High-entropy high-voltage electrolyte and preparation process thereof | 上海交通大学 | 2024-05-03 | — | — | CN | claimed |
| EP-0476645-B1 | Calcium uptake inhibitors | MERRELL DOW PHARMA (US) | 1995-09-06 | — | — | EP | claimed |
| EP-0476645-A1 | Calcium uptake inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-25 | — | — | EP | claimed |
| CN-117976988-A | High-entropy high-voltage electrolyte and preparation process thereof | 上海交通大学 | 2024-05-03 | — | — | CN | disclosed |
| US-11814462-B2 | Functionalized cyclic polymers and methods of preparing same | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| CN-115073401-B | 2,3 '-bisfuran compound, 2,3' -oligomeric furan compound, and preparation methods and applications thereof | 华南理工大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-115073401-A | 2,3 '-difuran compound and 2,3' -oligofuran compound, and preparation method and application thereof | 华南理工大学 | 2022-09-20 | — | — | CN | disclosed |
| US-20220127215-A1 | A COPPER-CATALYZED METHOD AND APPLICATION FOR PREPARING ALDEHYDES OR KETONES BY OXIDIZING ALCOHOLS WITH OXYGEN AS AN OXIDANT | FUDAN UNIVERSITY (CN) | 2022-04-28 | — | — | US | disclosed |
| US-20220056167-A1 | Functionalized Cyclic Polymers and Methods of Preparing Same | NATIONAL SCIENCE FOUNDATION | 2022-02-24 | — | — | US | disclosed |
| EP-3919469-A1 | COPPER-CATALYZED METHOD FOR PREPARING ALDEHYDE OR KETONE COMPOUND BY OXIDIZING ALCOHOL BY USING OXYGEN AS OXIDANT, AND APPLICATION THEREOF | Fudan University (CN) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020223672-A1 | FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME | UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) | 2020-11-05 | — | — | WO | disclosed |
| EP-2599765-A1 | PROCESS FOR PRODUCING ALDEHYDES OR KETONES BY OXIDIZING ALCOHOLS WITH OXYGEN | East China Normal University (CN) | 2013-06-05 | — | — | EP | disclosed |
| US-20120220792-A1 | PROCESS FOR PRODUCING ALDEHYDES OR KETONES BY OXIDIZING ALCOHOLS WITH OXYGEN | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2012-08-30 | — | — | US | disclosed |
| US-20120220792-A1 | PROCESS FOR PRODUCING ALDEHYDES OR KETONES BY OXIDIZING ALCOHOLS WITH OXYGEN | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2012-08-30 | — | — | US | disclosed |
| US-7763734-B2 | Synthesis, structure and use of bisoxazolidines for asymmetric catalysis and synthesis | GEORGETOWN UNIVERSITY (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070265255-A1 | SYNTHESIS, STRUCTURE AND USE OF BISOXAZOLIDINES FOR ASYMMETRIC CATALYSIS AND SYNTHESIS | GEORGETOWN UNIVERSITY | 2007-11-15 | — | — | US | disclosed |
| EP-0476645-B1 | Calcium uptake inhibitors | MERRELL DOW PHARMA (US) | 1995-09-06 | — | — | EP | disclosed |
| US-5409942-A | Administering 1-phenyl-3-aryl-2-propyne-1-ones compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-04-25 | — | — | US | disclosed |
| US-5223518-A | Controlling intake in leukocytes and platelets | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0476645-A1 | Calcium uptake inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220792-A1 | PROCESS FOR PRODUCING ALDEHYDES OR KETONES BY OXIDIZING ALCOHOLS WITH OXYGEN | ADH1C, NOX4, NOX1 | CACNA2D1 3015/4885CACNB2 2346/4885CACNA1C 1375/4885 |
| US-20220127215-A1 | A COPPER-CATALYZED METHOD AND APPLICATION FOR PREPARING ALDEHYDES OR KETONES BY OXIDIZING ALCOHOLS WITH OXYGEN AS AN OXIDANT | SOD1, ALDH2, AOC2 | CACNA2D1 3327/4885CACNB2 1583/4885CACNA1C 1152/4885 |
| US-20070265255-A1 | SYNTHESIS, STRUCTURE AND USE OF BISOXAZOLIDINES FOR ASYMMETRIC CATALYSIS AND SYNTHESIS | ADH5, ADH1C, ADH1A | CACNA2D1 2691/4885CACNB2 3433/4885CACNA1C 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.