SCHEMBL17767261

SCHEMBL17767261

O=C1c2ccoc2C(=O)c2c1ccc1ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.53
PTPRC P08575 1/20 0.47
ALDH1A1 P00352 6/20 0.47
MAPT P10636 3/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CES1 P23141 3/20 0.41
KDM4E B2RXH2 3/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 2/20 0.38
MAPK1 P28482 2/20 0.38
USP2 O75604 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30570716 1.00 DNMT1 (0.53) DNMT1PTPRCALDH1A1MAPTRAB9A
SCHEMBL3333300 0.87 DNMT1 (0.62) DNMT1PTPRCALDH1A1MAPTRAB9A
SCHEMBL27927489 0.86 DNMT1 (0.60) DNMT1PTPRCALDH1A1MAPTRAB9A
SCHEMBL9900718 0.80 DNMT1 (0.70) DNMT1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL12236188 0.78 DNMT1 (0.67) DNMT1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL30362207 0.78 DNMT1 (0.67) DNMT1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL7122517 0.78 DNMT1 (0.73) DNMT1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL183078 0.77 DNMT1 (0.78) DNMT1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL29612224 0.77 DNMT1 (0.78) DNMT1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL29358121 0.77 DNMT1 (0.78) DNMT1ALDH1A1MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4296365-B1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID VISOLIS INC (US) 2026-04-15 EP disclosed
EP-4296365-A2 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID Visolis, Inc. (US) 2023-12-27 EP disclosed
EP-3224368-B1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID VISOLIS INC (US) 2023-10-25 EP disclosed
US-11492339-B2 Processes for conversion of biologically derived mevalonic acid Visolis, Inc. (US) 2022-11-08 US disclosed
US-20210078966-A1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID Visolis, Inc. 2021-03-18 US disclosed
US-10807963-B2 Processes for conversion of biologically derived mevalonic acid Visolis, Inc. (US) 2020-10-20 US disclosed
US-20190169153-A1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID Visolis, Inc. 2019-06-06 US disclosed
US-10208008-B2 Processes for conversion of biologically derived mevalonic acid Visolis, Inc. (US) 2019-02-19 US disclosed
EP-3224368-A1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID Visolis, Inc. (US) 2017-10-04 EP disclosed
WO-2016085987-A1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID Visolis, Inc. (US) 2016-06-02 WO disclosed
US-20160145227-A1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID Visolis, Inc. 2016-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492339-B2 Processes for conversion of biologically derived mevalonic acid COASY, FDPS, ME1 DNMT1 2058/4885PTPRC 3980/4885ALDH1A1 1439/4885
US-20160145227-A1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID COASY, FDPS, GGPS1 DNMT1 2104/4885PTPRC 3666/4885ALDH1A1 1218/4885
US-20190169153-A1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID COASY, FDPS, GGPS1 DNMT1 2104/4885PTPRC 3666/4885ALDH1A1 1218/4885
US-10208008-B2 Processes for conversion of biologically derived mevalonic acid COASY, FDPS, ME1 DNMT1 2058/4885PTPRC 3980/4885ALDH1A1 1439/4885
US-10807963-B2 Processes for conversion of biologically derived mevalonic acid COASY, FDPS, ME1 DNMT1 2058/4885PTPRC 3980/4885ALDH1A1 1439/4885
US-20210078966-A1 PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID COASY, FDPS, ME1 DNMT1 2058/4885PTPRC 3980/4885ALDH1A1 1439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.