SCHEMBL17767378

SCHEMBL17767378

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nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1788967 0.90 PAX8 (0.41) PAX8
SCHEMBL9617279 0.84 PAX8 (0.38) PAX8
SCHEMBL2223107 0.84 PAX8 (0.38) PAX8
SCHEMBL1182041 0.84 PAX8 (0.38) PAX8
SCHEMBL424017 0.82 MPI (0.35)
SCHEMBL9807659 0.82 PAX8 (0.36) PAX8
SCHEMBL20889 0.82 PAX8 (0.36) PAX8
SCHEMBL2195882 0.81 PAX8 (0.36) PAX8
SCHEMBL17767400 0.81 PAX8 (0.36) PAX8
SCHEMBL16429714 0.81 PAX8 (0.35) PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250144021-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2025-05-08 US disclosed
US-12226527-B2 Gel formulations for local drug release TECHNICAL UNIVERSITY OF DENMARK (DK) 2025-02-18 US disclosed
CN-115501172-A Gel formulations for topical drug delivery 丹麦技术大学 2022-12-23 CN disclosed
CN-107249570-B Gel formulations for topical drug delivery 丹麦技术大学 2022-08-09 CN disclosed
US-20210386669-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2021-12-16 US disclosed
US-11065201-B2 Gel formulations for local drug release TECHNICAL UNIVERSITY OF DENMARK (DK) 2021-07-20 US disclosed
US-20180325819-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2018-11-15 US disclosed
EP-3220887-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE Technical University of Denmark (DK) 2017-09-27 EP disclosed
WO-2016079331-A1 GEL FORMULATIONS FOR ENHANCING THE EFFECT OF RADIOTHERAPY TECHNICAL UNIVERSITY OF DENMARK (DK) 2016-05-26 WO disclosed
WO-2016079332-A1 GEL FORMULATIONS FOR IMPROVING IMMUNOTHERAPY TECHNICAL UNIVERSITY OF DENMARK (DK) 2016-05-26 WO disclosed
WO-2016079330-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2016-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11065201-B2 Gel formulations for local drug release TREH, GALE, SLC2A8 PAX8 1105/4885
US-20180325819-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TREH, GALE, SLC2A8 PAX8 1105/4885
US-20250144021-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TREH, GALE, SLC2A8 PAX8 1105/4885
US-20210386669-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TREH, GALE, SLC2A8 PAX8 1105/4885
US-12226527-B2 Gel formulations for local drug release TREH, GALE, SLC2A8 PAX8 1105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.