SCHEMBL1788967

SCHEMBL1788967

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nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17767378 0.90 PAX8 (0.41) PAX8
SCHEMBL2223107 0.84 PAX8 (0.38) PAX8
SCHEMBL1182041 0.84 PAX8 (0.38) PAX8
SCHEMBL9617279 0.84 PAX8 (0.38) PAX8
SCHEMBL8937118 0.82 MPI (0.35)
SCHEMBL6863025 0.82 MPI (0.35)
SCHEMBL9807659 0.82 PAX8 (0.36) PAX8
SCHEMBL20889 0.82 PAX8 (0.36) PAX8
SCHEMBL2195882 0.81 PAX8 (0.36) PAX8
SCHEMBL17767400 0.81 PAX8 (0.36) PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115141866-B Preparation method of glucosamine salt 中国科学院海洋研究所 2023-10-31 CN claimed
CN-115141866-A Preparation method of glucosamine salt 中国科学院海洋研究所 2022-10-04 CN claimed
US-7138149-B2 Dietary supplements and methods for treating pain and inflammation MELALEUCA, INC. (US) 2006-11-21 US claimed
US-20040228884-A1 Ion-pair delivery system for cosmetic and pharmaceutical compositions GUPTA SHYAM K (US) 2004-11-18 US claimed
US-20040185035-A1 Dietary supplements and methods for treating pain and inflammation MELALEUCA, INC., AN IDAHO CORPORATION 2004-09-23 US claimed
US-20040156873-A1 Topically Bioavailable Acne and Rosacea Treatment Compositions GUPTA SHYAM K (US) 2004-08-12 US claimed
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions GUPTA SHYAM K (US) 2004-05-13 US claimed
US-6713096-B2 FOR REDUCING PAIN, INFLAMMATION, STIFFNESS, OR DISCOMFORT IN A MAMMAL MELALEUCA, INC. 2004-03-30 US claimed
US-20030143292-A1 For reducing pain, inflammation, stiffness, or discomfort in a mammal MELALEUCA, INC. 2003-07-31 US claimed
US-5681686-A BASIC ALUMINUM CHLORIDE AND GLUCOSAMINE SALT IWATSU ELECTRIC CO., LTD (JP) 1997-10-28 US claimed
CN-115141866-B Preparation method of glucosamine salt 中国科学院海洋研究所 2023-10-31 CN disclosed
CN-115141866-A Preparation method of glucosamine salt 中国科学院海洋研究所 2022-10-04 CN disclosed
US-10813868-B2 Method of improving hair volume CONOPCO, INC. (US) 2020-10-27 US disclosed
EP-3218062-B1 METHOD OF IMPROVING HAIR VOLUME UNILEVER PLC (GB) 2019-09-18 EP disclosed
CN-106137862-B Composition and cosmetics containing nano Chinese angelica 南京谷润生物科技有限公司 2019-03-08 CN disclosed
EP-1452546-A2 Poly-beta-1,4-N-Acetyglucosamine MARINE POLYMER TECHNOLOGIES, INC. (US) 2004-09-01 EP disclosed
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions GUPTA SHYAM K (US) 2004-05-13 US disclosed
US-6713096-B2 FOR REDUCING PAIN, INFLAMMATION, STIFFNESS, OR DISCOMFORT IN A MAMMAL MELALEUCA, INC. 2004-03-30 US disclosed
US-20030143292-A1 For reducing pain, inflammation, stiffness, or discomfort in a mammal MELALEUCA, INC. 2003-07-31 US disclosed
US-5681686-A BASIC ALUMINUM CHLORIDE AND GLUCOSAMINE SALT IWATSU ELECTRIC CO., LTD (JP) 1997-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions CUTA, HIRA, HARS1 PAX8 3014/4885
US-20030143292-A1 For reducing pain, inflammation, stiffness, or discomfort in a mammal TNF, IL6, IL1B PAX8 2064/4885
US-10813868-B2 Method of improving hair volume NACA, FTH1, FSCN1 PAX8 1173/4885
US-20040185035-A1 Dietary supplements and methods for treating pain and inflammation IL6, TNF, IL1B PAX8 806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.