Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.41 |
| ▸ | HTR1B | P28222 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1775834 | 0.99 | MALT1 (0.47) | MALT1HTR6ALDH1A1NPSR1TSHR | |
| SCHEMBL1775048 | 0.90 | HTR6 (0.49) | MALT1HTR6ALDH1A1NPSR1TSHR | |
| Hydrochloric Acid SCHEMBL1773877 | 0.90 | HTR6 (0.48) | MALT1HTR6ALDH1A1NPSR1TSHR | |
| SCHEMBL1775413 | 0.86 | MALT1 (0.48) | MALT1BRD4 | |
| SCHEMBL1775401 | 0.78 | HRH4 (0.45) | HTR6ALDH1A1LMNAMAPK1HTR2A | |
| SCHEMBL1774608 | 0.78 | HTR6 (0.51) | HTR6ALDH1A1TP53LMNAMAPK1 | |
| SCHEMBL1775441 | 0.77 | HTR6 (0.45) | MALT1HTR6NPSR1HTTHTR2A | |
| Hydrochloric Acid SCHEMBL1774702 | 0.77 | HRH4 (0.44) | HTR6ALDH1A1LMNAMAPK1HTR2A | |
| Hydrochloric Acid SCHEMBL1775137 | 0.77 | HTR6 (0.50) | HTR6ALDH1A1TP53LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL1775491 | 0.76 | HTR6 (0.45) | HTR6NPSR1HTTHTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |