Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.60 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16079565 | 0.91 | TSHR (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL16079575 | 0.87 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL17772764 | 0.87 | TSHR (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL17772763 | 0.87 | TSHR (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL16079574 | 0.86 | TRPC4 (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL16029320 | 0.86 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL16079560 | 0.85 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL16079561 | 0.85 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AHIF1A | |
| Hydrochloric Acid SCHEMBL16031117 | 0.84 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MEN1KMT2AHIF1A | |
| Hydrochloric Acid SCHEMBL16030824 | 0.84 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160145257-A1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, INC. | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145257-A1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | TRPC5, TRPC7, TRPC4 | ALDH1A1 1647/4885SMN1; SMN2 1307/4885MEN1 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.