SCHEMBL17775111

SCHEMBL17775111

COc1ccc(-c2cc(F)c(-c3ccc(C)cc3)c(F)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.54
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.47
MAPK1 P28482 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
MAPT P10636 2/20 0.46
ATM Q13315 1/20 0.46
KMT2A Q03164 2/20 0.46
ABL1 P00519 1/20 0.44
ABCB1 P08183 1/20 0.44
BCR P11274 1/20 0.44
RELA Q04206 1/20 0.44
ALOX5 P09917 2/20 0.44
MEN1 O00255 1/20 0.43
CYP11B1 P15538 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17942997 0.87 ACHE (0.42) ACHEKMT2AMEN1CYP11B1CYP11B2
SCHEMBL13791094 0.81 NPC1 (0.53) ACHENPC1RAB9ASMN1; SMN2TP53
SCHEMBL17775114 0.81 NPC1 (0.53) ACHENPC1RAB9ASMN1; SMN2TP53
SCHEMBL12696827 0.81 ACHE (0.54) ACHENPC1RAB9ASMN1; SMN2MAPT
SCHEMBL18559416 0.81 ACHE (0.52) ACHENPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL16183020 0.81 ACHE (0.52) ACHENPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL12714843 0.80 ACHE (0.83) ACHENPC1RAB9ASMN1; SMN2TP53
SCHEMBL16748059 0.80 SQOR (0.47) NPC1RAB9ASMN1; SMN2TP53MAPK1
SCHEMBL3676881 0.80 ACHE (0.83) ACHENPC1RAB9ASMN1; SMN2TP53
SCHEMBL295716 0.80 ACHE (0.83) ACHENPC1RAB9ASMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10174184-B2 Cellulosic material, liquid composition, shaped article, and shaped article production method SEIKO EPSON CORPORATION (JP) 2019-01-08 US disclosed
US-9796790-B2 Liquid composition, shaped article, and shaped article production method SEIKO EPSON CORPORATION (JP) 2017-10-24 US disclosed
US-9796790-B2 Liquid composition, shaped article, and shaped article production method SEIKO EPSON CORPORATION (JP) 2017-10-24 US disclosed
US-20160289481-A1 COMPOSITION SET, SHAPED ARTICLE PRODUCTION METHOD, AND SHAPED ARTICLE SEIKO EPSON CORPORATION (JP) 2016-10-06 US disclosed
US-20160289481-A1 COMPOSITION SET, SHAPED ARTICLE PRODUCTION METHOD, AND SHAPED ARTICLE SEIKO EPSON CORPORATION (JP) 2016-10-06 US disclosed
EP-3075746-A1 COMPOSITION SET, SHAPED ARTICLE PRODUCTION METHOD, AND SHAPED ARTICLE Seiko Epson Corporation (JP) 2016-10-05 EP disclosed
US-20160280948-A1 COMPOSITION, SHAPED ARTICLE PRODUCTION METHOD, AND SHAPED ARTICLE SEIKO EPSON CORPORATION (JP) 2016-09-29 US disclosed
US-20160280948-A1 COMPOSITION, SHAPED ARTICLE PRODUCTION METHOD, AND SHAPED ARTICLE SEIKO EPSON CORPORATION (JP) 2016-09-29 US disclosed
EP-3072923-A1 COMPOSITION, SHAPED ARTICLE PRODUCTION METHOD, AND SHAPED ARTICLE Seiko Epson Corporation (JP) 2016-09-28 EP disclosed
US-20160145422-A1 CELLULOSIC MATERIAL, LIQUID COMPOSITION, SHAPED ARTICLE, AND SHAPED ARTICLE PRODUCTION METHOD SEIKO EPSON CORPORATION (JP) 2016-05-26 US disclosed
US-20160145422-A1 CELLULOSIC MATERIAL, LIQUID COMPOSITION, SHAPED ARTICLE, AND SHAPED ARTICLE PRODUCTION METHOD SEIKO EPSON CORPORATION (JP) 2016-05-26 US disclosed
US-20160145455-A1 LIQUID COMPOSITION, SHAPED ARTICLE, AND SHAPED ARTICLE PRODUCTION METHOD SEIKO EPSON CORPORATION (JP) 2016-05-26 US disclosed
US-20160145455-A1 LIQUID COMPOSITION, SHAPED ARTICLE, AND SHAPED ARTICLE PRODUCTION METHOD SEIKO EPSON CORPORATION (JP) 2016-05-26 US disclosed