Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salsolidine SCHEMBL34461883 | 1.00 | MAOA (1.00) | MAOATSHRALDH1A1HSD17B10CYP2D6 | |
| Salsolidine SCHEMBL4250569 | 1.00 | MAOA (1.00) | MAOATSHRALDH1A1HSD17B10CYP2D6 | |
| Salsolidine SCHEMBL1819825 | 1.00 | MAOA (1.00) | MAOATSHRALDH1A1HSD17B10CYP2D6 | |
| Salsolidine SCHEMBL5242077 | 0.98 | MAOA (1.00) | MAOATSHRALDH1A1HSD17B10CYP2D6 | |
| Salsolidine SCHEMBL7838872 | 0.98 | MAOA (0.97) | MAOATSHRALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL7852877 | 0.90 | MAOA (0.81) | MAOATSHRALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL7848778 | 0.88 | MAOA (0.79) | MAOATSHRALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL7848489 | 0.87 | MAOA (0.77) | MAOATSHRALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL7847453 | 0.87 | MAOA (0.77) | MAOATSHRALDH1A1HSD17B10CYP2D6 | |
| Salsoline SCHEMBL20485120 | 0.87 | MAOA (1.00) | MAOATSHRALDH1A1HSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12569483-B2 | Methods for objective assessment of memory, early detection of risk for Alzheimer's disease, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2026-03-10 | — | — | US | claimed |
| US-20220211700-A1 | Methods for Objective Assessment of Memory, Early Detection of Risk for Alzheimer's Disease, Matching Individuals With Treatments, Monitoring Response to Treatment, and New Methods of Use for Drugs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-07-07 | — | — | US | claimed |
| EP-3972975-A1 | METHODS FOR OBJECTIVE ASSESSMENT OF MEMORY, EARLY DETECTION OF RISK FOR ALZHEIMER'S DISEASE, MATCHING INDIVIDUALS WITH TREATMENTS, MONITORING RESPONSE TO TREATMENT, AND NEW METHODS OF USE FOR DRUGS | Indiana University Research and Technology Corporation (US) | 2022-03-30 | — | — | EP | claimed |
| WO-2020237203-A1 | METHODS FOR OBJECTIVE ASSESSMENT OF MEMORY, EARLY DETECTION OF RISK FOR ALZHEIMER'S DISEASE, MATCHING INDIVIDUALS WITH TREATMENTS, MONITORING RESPONSE TO TREATMENT, AND NEW METHODS OF USE FOR DRUGS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2020-11-26 | — | — | WO | claimed |
| EP-2001877-A1 | METHOD FOR EXTRACTING TARGET ALKALOID USING AN IONIC LIQUID AS EXTRACTING SOLVENT | Bioniqs Limited (GB) | 2008-12-17 | — | — | EP | claimed |
| WO-2007110637-A1 | METHOD FOR EXTRACTING TARGET ALKALOID USING AN IONIC LIQUID AS EXTRACTING SOLVENT | BIONIQS LIMITED (GB) | 2007-10-04 | — | — | WO | claimed |
| US-12569483-B2 | Methods for objective assessment of memory, early detection of risk for Alzheimer's disease, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2026-03-10 | — | — | US | disclosed |
| EP-4140974-B1 | METHODS OF IRON CATALYZED C-H BOND AMINATION | VERSITECH LTD (CN) | 2025-05-14 | — | — | EP | disclosed |
| CN-119661514-A | Herba corydalis Bungeanae total alkaloid extract for preventing and treating hyperuricemia, and preparation method and application thereof | 云南中医药大学 | 2025-03-21 | — | — | CN | disclosed |
| US-12098126-B2 | Methods of iron catalyzed C-H bond amination | VERSITECH LIMITED (CN) | 2024-09-24 | — | — | US | disclosed |
| CN-118146154-A | Method for synergistic catalysis of selective oxidative dehydrogenation of tetrahydroisoquinoline | 西安石油大学 | 2024-06-07 | — | — | CN | disclosed |
| US-20240052418-A1 | METHOD FOR PREDICTING A SUBJECT'S RESPONSE TO SLC MODULATOR THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-02-15 | — | — | US | disclosed |
| CN-115124466-B | Synthesis method of tetrahydropapaverine hydrochloride | 浙江博崤生物制药有限公司 | 2024-01-12 | — | — | CN | disclosed |
| US-4766131-A | 2-amino (or hydroxy) phenethyl-1,2,3,4-tetrahydroisoquinolines as analgesics | PENNWALT CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |
| WO-1987007508-A1 | METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1987-12-17 | — | — | WO | disclosed |
| EP-0245960-A2 | Process for preparing N-acyltetrahydroisoquinoline | Takasago Perfumery Co., Ltd. (JP) | 1987-11-19 | — | — | EP | disclosed |
| EP-0083612-A1 | NEW DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PREPARATION THEREOF AND UTILIZATION THEREOF AS DRUGS | FLORK, Michel (FR) | 1983-07-20 | — | — | EP | disclosed |
| WO-1983000146-A1 | NEW DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PREPARATION THEREOF AND UTILIZATION THEREOF AS DRUGS | FLORK, MICHEL | 1983-01-20 | — | — | WO | disclosed |
| US-4365064-A | VASODILATORS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1982-12-21 | — | — | US | disclosed |
| EP-0051190-A2 | N-(amino(or hydroxy) phenethyl)-1,2,3,4-tetrahydroisoquinolines, precursors thereof, and methods of preparation | PENNWALT CORPORATION (US) | 1982-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12098126-B2 | Methods of iron catalyzed C-H bond amination | FTH1, FECH, HCCS | MAOA 45/4885TSHR 1353/4885ALDH1A1 938/4885 |
| US-12569483-B2 | Methods for objective assessment of memory, early detection of risk for Alzheimer's disease, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs | PSMB3, THRB, GRIN2B | MAOA 1920/4885TSHR 728/4885ALDH1A1 4257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.