Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17767286 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TDP1LMNASLC15A2GAA | |
| SCHEMBL17767284 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TDP1LMNASLC15A2GAA | |
| SCHEMBL1406314 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNASLC15A2GAA | |
| SCHEMBL2851364 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TDP1LMNASLC15A2MEN1 | |
| SCHEMBL29271678 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNASLC15A2GAA | |
| SCHEMBL31016295 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNASLC15A2GAAACHE | |
| SCHEMBL1406644 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TDP1LMNAGAACES2 | |
| SCHEMBL17779668 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNACES2MEN1 | |
| SCHEMBL1406218 | 0.76 | CYP1A2 (0.44) | ALDH1A1TDP1LMNAGAAMEN1 | |
| SCHEMBL29271676 | 0.76 | MEN1 (0.47) | ALDH1A1LMNAGAAMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160145273-A1 | PRECATALYST FOR SHIBASAKI'S RARE EARTH METAL BINOLATE CATALYSTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145273-A1 | PRECATALYST FOR SHIBASAKI'S RARE EARTH METAL BINOLATE CATALYSTS | TBCB, RUVBL2, RHEB | ALDH1A1 3983/4885TDP1 4305/4885LMNA 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.