Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.52 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD5 | P21918 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18745412 | 0.85 | CYP11B2 (0.56) | CYP11B2DRD2DRD3CHRNA7CHRNB2 | |
| SCHEMBL17774405 | 0.85 | CYP11B2 (0.53) | CYP11B2DRD2DRD3CHRNA7CHRNB2 | |
| SCHEMBL23374726 | 0.84 | CYP11B2 (0.53) | CYP11B2CHRNA7CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL13842724 | 0.83 | CYP11B2 (0.57) | CYP11B2DRD2CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL17518822 | 0.82 | CYP11B2 (0.60) | CYP11B2DRD2DRD3CHRNA7CHRNB2 | |
| SCHEMBL16410879 | 0.81 | DRD2 (0.54) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL12125697 | 0.81 | DRD2 (0.76) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL12125694 | 0.81 | DRD2 (0.76) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL10644222 | 0.81 | DRD2 (0.76) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL16144645 | 0.80 | HSD11B1 (0.50) | CYP11B2CHRNA7CHRNB2CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624211-B2 | Anti-cancer compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-04-18 | — | — | US | disclosed |
| US-20160145250-A1 | ANTI-CANCER COMPOUNDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145250-A1 | ANTI-CANCER COMPOUNDS | SKP2, TP53, TEAD2 | CYP11B2 2344/4885DRD2 3791/4885DRD3 3537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.