Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 4/20 | 0.41 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666528 | 0.80 | ADRA2C (0.55) | ADRA2CABL1PRKCALMNARAF1 | |
| SCHEMBL29666526 | 0.80 | ADRA2C (0.55) | ADRA2CABL1PRKCALMNARAF1 | |
| SCHEMBL18533934 | 0.78 | LMNA (0.50) | ABL1PRKCAKMOLMNARAF1 | |
| SCHEMBL17646086 | 0.77 | KDR (0.51) | ADRA2CABL1PRKCALMNAMAPK1 | |
| SCHEMBL24911411 | 0.77 | SIRT2 (0.55) | CYP3A4SIRT2SIRT1CNR1SYK | |
| SCHEMBL20317131 | 0.77 | SIRT2 (0.55) | CYP3A4SIRT2SIRT1CNR1SYK | |
| SCHEMBL28226596 | 0.76 | ALK (0.49) | SIRT2SIRT1CNR1SYKPRKCI | |
| SCHEMBL16383523 | 0.76 | ADRA2C (0.48) | ADRA2CABL1PRKCALMNARAF1 | |
| SCHEMBL17779640 | 0.76 | SIRT2 (0.48) | PRKCALMNACYP1A2CYP3A4MAPK1 | |
| SCHEMBL17779594 | 0.76 | ALK (0.41) | PRKCALMNAL3MBTL1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079667-A1 | INDOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS | IDEMITSU KOSAN CO., LTD. (JP) | 2016-05-26 | — | — | WO | disclosed |