Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666528 | 0.89 | ADRA2C (0.55) | ADRA2CCYP1A2CYP3A4ALDH1A1CYP2A6 | |
| SCHEMBL29666526 | 0.89 | ADRA2C (0.55) | ADRA2CCYP1A2CYP3A4ALDH1A1CYP2A6 | |
| SCHEMBL17646086 | 0.85 | KDR (0.51) | ADRA2CALDH1A1NPC1RAB9AABL1 | |
| SCHEMBL15158543 | 0.85 | CYP1A2 (0.60) | CYP1A2CYP3A4ALDH1A1CYP2A6MKNK1 | |
| SCHEMBL23111305 | 0.85 | FABP3 (0.52) | CYP1A2CYP3A4ALDH1A1NPC1RAB9A | |
| SCHEMBL15549870 | 0.85 | FABP3 (0.52) | CYP1A2CYP3A4ALDH1A1NPC1RAB9A | |
| SCHEMBL17733473 | 0.85 | FABP3 (0.52) | CYP1A2CYP3A4ALDH1A1NPC1RAB9A | |
| SCHEMBL5457659 | 0.85 | FABP3 (0.52) | CYP1A2CYP3A4ALDH1A1NPC1RAB9A | |
| SCHEMBL24057710 | 0.85 | FABP3 (0.52) | CYP1A2CYP3A4ALDH1A1NPC1RAB9A | |
| SCHEMBL4428807 | 0.85 | FABP3 (0.52) | CYP1A2CYP3A4ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220165961-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-05-26 | — | — | US | disclosed |
| EP-3218368-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| US-10651389-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2020-05-12 | — | — | US | disclosed |
| EP-3017016-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-04-15 | — | — | EP | disclosed |
| US-10577342-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-03-03 | — | — | US | disclosed |
| US-20200048207-A1 | COMPOUNDS WITH ARYLAMINE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-02-13 | — | — | US | disclosed |
| EP-3174954-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-02-13 | — | — | EP | disclosed |
| US-20170207399-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-07-20 | — | — | US | disclosed |
| US-20170207399-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-07-20 | — | — | US | disclosed |
| WO-2016074755-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-05-19 | — | — | WO | disclosed |
| US-20160141508-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-05-19 | — | — | US | disclosed |
| US-20160141508-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-05-19 | — | — | US | disclosed |
| WO-2016015810-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |
| WO-2015000549-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10651389-B2 | Materials for electronic devices | EFNA1, NES, EED | ADRA2C 3945/4885CYP1A2 223/4885CYP3A4 798/4885 |
| US-20160141508-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, NES, EED | ADRA2C 3945/4885CYP1A2 223/4885CYP3A4 798/4885 |
| US-20170207399-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, ESD, TST | ADRA2C 4567/4885CYP1A2 2369/4885CYP3A4 2239/4885 |
| US-20200048207-A1 | COMPOUNDS WITH ARYLAMINE STRUCTURES | DDT, NAT1, INMT | ADRA2C 299/4885CYP1A2 64/4885CYP3A4 108/4885 |
| US-20220165961-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, ESD, TST | ADRA2C 4567/4885CYP1A2 2369/4885CYP3A4 2239/4885 |
| US-10577342-B2 | Materials for organic electroluminescent devices | PIEZO1, L1CAM, EFNA1 | ADRA2C 3381/4885CYP1A2 528/4885CYP3A4 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.