SCHEMBL177826

SCHEMBL177826

C=C(C(N)=O)C(CC)S(=O)(=O)O.[NaH]

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1472171 0.98 TDP1 (0.33) TDP1RECQL
SCHEMBL2784998 0.86 HDAC1 (0.35) TDP1RECQL
SCHEMBL177995 0.84 HDAC1 (0.37) TDP1RECQL
SCHEMBL9515820 0.84 RECQL (0.34) RECQL
SCHEMBL29291030 0.82 RECQL (0.32) RECQL
SCHEMBL307519 0.79 RECQL (0.33) TDP1RECQL
Potassium Ion SCHEMBL1025779 0.78 CYP3A4 (0.32) RECQL
SCHEMBL28325083 0.78 RECQL (0.32) RECQL
SCHEMBL15453388 0.77 TDP1 (0.30) TDP1
SCHEMBL10500021 0.76 CA1 (0.37) RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2386538-B1 N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME SHOWA DENKO KK (JP) 2015-07-29 EP disclosed
US-8697912-B2 N-(1-hydroxyethyl) carboxamide compound and process for producing same SHOWA DENKO K.K. (JP) 2014-04-15 US disclosed
US-20110294974-A1 N-(1-HYDROXYETHYL ) CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME SHOWA DENKO K.K. (JP) 2011-12-01 US disclosed
EP-2386538-A1 N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME Showa Denko K.K. (JP) 2011-11-16 EP disclosed
EP-0812311-B1 HIGHLY POLYMERIZABLE N-VINYLCARBOXYLIC ACID AMIDE AND PRODUCTION PROCESS THEREOF SHOWA DENKO KK (JP) 2002-03-20 EP disclosed
EP-0473881-B1 Liquid absorption agent SHOWA DENKO KK (JP) 2001-11-07 EP disclosed
US-6166253-A Process for producing N-(1-alkoxyethyl)carboxylic amides SHOWA DENKO K.K. (JP) 2000-12-26 US disclosed
US-6153708-A HAVING AN N-1,3-BUTADIENYLCARBOXYLIC ACID AMIDE CONTENT OF 30 PPM OR LESS. SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-11-28 US disclosed
US-6143836-A PRODUCING HOMOPOLYMER OR COPOLYMER OF N-VINYLCARBOXYLIC ACID AMIDE BY POLYMERIZING HIGHLY POLYMERIZABLE N-VINYLCARBOXYLIC ACID AMIDE HAVING N-1,3-BUTADIENYLCARBOXYLIC ACID AMIDE CONTENT OF 30 PPM OR LESS; USE AS THICKENER SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-11-07 US disclosed
EP-0799820-B1 Process producing n-(1-alkoxyethyl)carboxylic amides SHOWA DENKO KK (JP) 2000-11-02 EP disclosed
US-5789619-A USED AS COAGULANTS, LIQUID ABSORBENTS, THICKENERS SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-08-04 US disclosed
US-5744118-A MIXING ABSORBENT RESIN AND METAL SALTS, SWELLING AND GELATION, ADJUSTMENT OF PH, PYROLYSIS AND ROASTING SHOWA DENKO K.K. (JP) 1998-04-28 US disclosed
EP-0799820-A1 Process producing n-(1-alkoxyethyl)carboxylic amides SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-10-08 EP disclosed
EP-0510246-B1 Use of fine particulate crosslinked type n-vinylamide resin microgel SHOWA DENKO KK (JP) 1996-09-25 EP disclosed
US-5407996-A Contacting with an aqueous solution of metal ion or metal oxide to form a gel; calcining SHOWA DENKO K.K. (JP) 1995-04-18 US disclosed
US-5338815-A Used in thickeners, dispersion stabilizers and lubricants SHOWA DENKO K.K. (JP) 1994-08-16 US disclosed
US-5300606-A Crosslinked N-vinylamide resin SHOWA DENKO K.K. (JP) 1994-04-05 US disclosed
US-5280095-A N-vinylcarboxylic acid amine resin SHOWA DENKO K.K. (JP) 1994-01-18 US disclosed
EP-0510246-A1 Use of fine particulate crosslinked type n-vinylamide resin microgel SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-10-28 EP disclosed
EP-0473881-A1 Liquid absorption agent SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294974-A1 N-(1-HYDROXYETHYL ) CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME ADH1A, ADH1C, CNKSR1 TDP1 1472/4885RECQL 3397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.