Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586151 | 0.82 | ALDH1A1 (0.41) | ALDH1A1ALOX15TSHR | |
| SCHEMBL30166648 | 0.75 | ALDH1A1 (0.35) | ALDH1A1ALOX15TSHR | |
| SCHEMBL12599932 | 0.75 | ALDH1A1 (0.35) | ALDH1A1ALOX15TSHR | |
| SCHEMBL18913381 | 0.71 | CDK1 (0.33) | ALDH1A1ALOX15TSHR | |
| SCHEMBL10827853 | 0.71 | ALDH1A1 (0.41) | ALDH1A1ALOX15TSHR | |
| SCHEMBL12599922 | 0.68 | CYP1A2 (0.41) | ALDH1A1 | |
| SCHEMBL12599748 | 0.68 | LMNA (0.31) | — | |
| SCHEMBL20302639 | 0.68 | YTHDC1 (0.43) | — | |
| SCHEMBL28797302 | 0.67 | — | — | |
| SCHEMBL29344559 | 0.66 | ALDH1A1 (0.41) | ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518056-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160152614-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152614-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | ACE, IRF3, ACE2 | ALDH1A1 2831/4885ALOX15 2809/4885TSHR 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.