Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943546 | 0.95 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2ALDH1A1RECQLESR1 | |
| SCHEMBL26290184 | 0.91 | ESR1 (0.50) | CYP3A4SMN1; SMN2ALDH1A1ESR1ESR2 | |
| SCHEMBL17787403 | 0.87 | CYP3A4 (0.51) | CYP3A4SMN1; SMN2ALDH1A1RECQLESR1 | |
| SCHEMBL3004341 | 0.86 | ESR1 (0.45) | CYP3A4SMN1; SMN2ALDH1A1RECQLESR1 | |
| SCHEMBL12214816 | 0.84 | CYP3A4 (0.45) | CYP3A4SMN1; SMN2ALDH1A1RECQLESR1 | |
| SCHEMBL15890437 | 0.81 | ALDH1A1 (0.65) | CYP3A4SMN1; SMN2ALDH1A1RECQLNR1I2 | |
| SCHEMBL10606350 | 0.80 | CYP3A4 (0.62) | CYP3A4SMN1; SMN2ALDH1A1RECQLNR1I2 | |
| SCHEMBL584253 | 0.80 | CYP3A4 (0.58) | CYP3A4SMN1; SMN2ALDH1A1RECQLNR1I2 | |
| SCHEMBL5707301 | 0.79 | SMN1; SMN2 (0.62) | CYP3A4SMN1; SMN2ALDH1A1RECQLNR1I2 | |
| SCHEMBL15890450 | 0.79 | SMN1; SMN2 (0.62) | CYP3A4SMN1; SMN2ALDH1A1RECQLNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174833-A1 | HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-06-22 | — | — | US | disclosed |
| US-9353216-B2 | High-fluidity polycarbonate copolymer, process for production highly polymerized aromatic polycarbonate resin and aromatic polycarbonate compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-05-31 | — | — | US | disclosed |