Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 1/20 | 0.52 |
| ▸ | NMT1 | P30419 | 1/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | FURIN | P09958 | 9/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035292 | 0.89 | FURIN (0.52) | NMT2NMT1SIRT6SIRT1FURIN | |
| SCHEMBL20952056 | 0.89 | SIRT6 (0.51) | NMT2NMT1SIRT6SIRT1FURIN | |
| SCHEMBL20952057 | 0.89 | SIRT6 (0.51) | NMT2NMT1SIRT6SIRT1FURIN | |
| SCHEMBL22640914 | 0.87 | GRIN2D (0.46) | NMT2NMT1SIRT6SIRT1FURIN | |
| SCHEMBL16234720 | 0.87 | SIRT5 (0.58) | NMT2NMT1SIRT6SIRT1FURIN | |
| SCHEMBL14669744 | 0.87 | NMT2 (0.50) | NMT2NMT1SIRT6SIRT1FURIN | |
| SCHEMBL16234721 | 0.87 | SIRT5 (0.46) | NMT2NMT1SIRT6SIRT1FURIN | |
| SCHEMBL16259323 | 0.87 | NMT2 (0.53) | NMT2NMT1SIRT6SIRT1FURIN | |
| SCHEMBL16259340 | 0.87 | NMT2 (0.53) | NMT2NMT1SIRT6SIRT1FURIN | |
| SCHEMBL16234712 | 0.87 | NMT2 (0.53) | NMT2NMT1SIRT6SIRT1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353149-B2 | Compounds, compositions and methods for the treatment of diseases through inhibiting TGF-β activity | SOUTHERN RESEARCH INSTITUTE (US) | 2016-05-31 | — | — | US | disclosed |