Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17792653 | 1.00 | HTR2A (0.34) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL20198331 | 0.81 | CAMK2A (0.35) | OPRM1OPRD1OPRK1EDNRBEDNRA | |
| SCHEMBL18829648 | 0.74 | EDNRB (0.34) | EDNRBEDNRA | |
| SCHEMBL10043585 | 0.68 | KDM1A (0.33) | HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL6727229 | 0.68 | S100A4 (0.41) | EDNRBEDNRA | |
| SCHEMBL13298453 | 0.60 | METAP1 (0.45) | — | |
| SCHEMBL1819784 | 0.58 | KDM1A (0.41) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL18300734 | 0.58 | AHR (0.34) | HTR2AHTR2CHTR2BKDM1AEDNRB | |
| SCHEMBL12700844 | 0.58 | MEN1 (0.40) | HTR2B | |
| SCHEMBL16905177 | 0.57 | PTGDR (0.40) | HTR2AHTR2CHTR2BOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840514-B2 | Dianhydrides, polyimides, methods of making each, and methods of use | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2017-12-12 | — | — | US | disclosed |
| US-20160152630-A1 | DIANHYDRIDES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152630-A1 | DIANHYDRIDES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE | ALKBH3, ALK, DDC | HTR2A 2221/4885HTR2C 2176/4885HTR2B 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.