Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.56 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.56 |
| ▸ | EIF4A2 | Q14240 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17790599 | 1.00 | EIF4A3 (0.56) | EIF4A3EIF4A1EIF4A2LMNAGPBAR1 | |
| SCHEMBL17790606 | 1.00 | EIF4A3 (0.56) | EIF4A3EIF4A1EIF4A2LMNAGPBAR1 | |
| SCHEMBL17790604 | 1.00 | EIF4A3 (0.56) | EIF4A3EIF4A1EIF4A2LMNAGPBAR1 | |
| SCHEMBL17790603 | 1.00 | EIF4A3 (0.56) | EIF4A3EIF4A1EIF4A2LMNAGPBAR1 | |
| SCHEMBL17790607 | 1.00 | EIF4A3 (0.56) | EIF4A3EIF4A1EIF4A2LMNAGPBAR1 | |
| SCHEMBL14525637 | 0.88 | LMNA (0.68) | EIF4A3EIF4A1EIF4A2LMNAGPBAR1 | |
| SCHEMBL14416968 | 0.88 | LMNA (0.68) | EIF4A3EIF4A1EIF4A2LMNAGPBAR1 | |
| SCHEMBL14416971 | 0.88 | LMNA (0.68) | EIF4A3EIF4A1EIF4A2LMNAGPBAR1 | |
| SCHEMBL17361285 | 0.85 | LMNA (0.53) | EIF4A3EIF4A1EIF4A2LMNAGPBAR1 | |
| SCHEMBL20058543 | 0.85 | LMNA (0.53) | EIF4A3EIF4A1EIF4A2LMNAGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160152658-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152658-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | ADRA1B, AVPR1B, ADRA2B | EIF4A3 1339/4885EIF4A1 778/4885EIF4A2 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.