SCHEMBL17791126

SCHEMBL17791126

CCOc1ccc(-c2ccc(-c3ccc(CC)cc3)c(F)c2)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR2 P21802 2/20 0.41
▸ FGFR1 P11362 1/20 0.41
▸ PTPRC P08575 1/20 0.37
▸ FFAR4 Q5NUL3 1/20 0.37
▸ NAAA Q02083 1/20 0.37
▸ GABRA1 P14867 2/20 0.36
▸ GABRB2 P47870 2/20 0.36
▸ ALOX5AP P20292 1/20 0.36
▸ FEN1 P39748 1/20 0.36
▸ S1PR1 P21453 2/20 0.36
▸ S1PR3 Q99500 2/20 0.36
▸ PTGS2 P35354 4/20 0.35
▸ RXRA P19793 1/20 0.35
▸ RXRB P28702 1/20 0.35
▸ RXRG P48443 1/20 0.35
▸ RARB P10826 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10303329 0.93 FGFR2 (0.39) FGFR2FGFR1PTPRCFFAR4NAAA
SCHEMBL10091331 0.91 FGFR2 (0.40) FGFR2FGFR1PTPRCFFAR4GABRA1
SCHEMBL17791129 0.91 ALOX5AP (0.39) FGFR2FGFR1GABRA1GABRB2ALOX5AP
SCHEMBL16871137 0.90 FGFR2 (0.39) FGFR2FGFR1PTPRCFFAR4GABRA1
SCHEMBL22902900 0.90 FGFR2 (0.42) FGFR2FGFR1PTPRCFFAR4GABRA1
SCHEMBL17791134 0.89 CNR2 (0.42) FFAR4ALOX5APFEN1S1PR1S1PR3
SCHEMBL17637058 0.89 GABRA1 (0.43) FGFR2FGFR1PTPRCFFAR4NAAA
SCHEMBL17108434 0.89 FGFR2 (0.41) FGFR2FGFR1PTPRCFFAR4NAAA
SCHEMBL17791130 0.89 CYP17A1 (0.42) NAAAPTGS2PTGS1
SCHEMBL17791135 0.88 RARB (0.44) ALOX5APFEN1S1PR1S1PR3RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230333428-A1 LIQUID CRYSTAL DISPLAY DEVICE Sharp Display Technology Corporation (JP) 2023-10-19 — — US disclosed
US-20230183572-A1 LIQUID CRYSTAL COMPOSITION WITH GOOD FREQUENCY DEPENDENCE AND LIQUID CRYSTAL DISPLAY ELEMENT SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2023-06-15 — — US disclosed
US-20230183572-A1 LIQUID CRYSTAL COMPOSITION WITH GOOD FREQUENCY DEPENDENCE AND LIQUID CRYSTAL DISPLAY ELEMENT SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2023-06-15 — — US disclosed
US-20230167362-A1 NEGATIVE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT OR LIQUID CRYSTAL DISPLAY SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MAT CO ITD (CN) 2023-06-01 — — US disclosed
US-20230167362-A1 NEGATIVE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT OR LIQUID CRYSTAL DISPLAY SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MAT CO ITD (CN) 2023-06-01 — — US disclosed
US-10400169-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2019-09-03 — — US disclosed
US-10208251-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2019-02-19 — — US disclosed
US-20180030350-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-02-01 — — US disclosed
US-20180030350-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-02-01 — — US disclosed
US-20170044438-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-16 — — US disclosed
US-20170044438-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-16 — — US disclosed
US-20170044437-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-16 — — US disclosed
US-20170044437-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-16 — — US disclosed
US-20160152587-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2016-06-02 — — US disclosed
US-20160152587-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2016-06-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044438-A1 LIQUID-CRYSTALLINE MEDIUM VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885PTPRC 2173/4885
US-20180030350-A1 LIQUID-CRYSTALLINE MEDIUM VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885PTPRC 2173/4885
US-10400169-B2 Liquid-crystalline medium VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885PTPRC 2173/4885
US-20170044437-A1 LIQUID-CRYSTALLINE MEDIUM VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885PTPRC 2173/4885
US-10208251-B2 Liquid-crystalline medium VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885PTPRC 2173/4885
US-20160152587-A1 LIQUID-CRYSTALLINE MEDIUM VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885PTPRC 2173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback