SCHEMBL17792189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21991658	1.00	DGAT1 (0.40)	DGAT1SOAT1ITGB3ITGA2BDGAT2
	SCHEMBL17784015	0.94	DGAT1 (0.37)	DGAT1SOAT1ITGB3ITGA2BDGAT2
	SCHEMBL19473201	0.91	MAPK14 (0.40)	DGAT1SOAT1ITGB3ITGA2BRARA
	SCHEMBL17792190	0.87	NPC1 (0.50)	DGAT1NPC1RAB9AMAOBKCNQ3
	SCHEMBL17784148	0.86	NPC1 (0.39)	DGAT1SOAT1RARARARBRARG
	SCHEMBL17784096	0.86	NPC1 (0.39)	DGAT1SOAT1RARARARBRARG
	SCHEMBL17784094	0.86	NPC1 (0.39)	DGAT1SOAT1RARARARBRARG
	SCHEMBL17792077	0.85	LMNA (0.39)	RARARARBRARGNPC1RAB9A
	SCHEMBL17784130	0.85	NPC1 (0.45)	DGAT1SOAT1ITGB3ITGA2BDGAT2
	SCHEMBL17784102	0.85	MAPT (0.45)	RARARARBRARGNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.