SCHEMBL1779366

SCHEMBL1779366

N[C@H](CO)Cc1ccc(Cl)cc1

nearest known ligand 0.78

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.78
SLC6A2 P23975 1/20 0.59
SLC6A3 Q01959 1/20 0.59
DPP4 P27487 1/20 0.45
DPP7 Q9UHL4 1/20 0.45
EPHX1 P07099 1/20 0.44
NMT1 P30419 2/20 0.43
TAAR1 Q96RJ0 1/20 0.43
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
IDO1 P14902 4/20 0.41
AGXT P21549 2/20 0.41
ANPEP P15144 2/20 0.40
ENPEP Q07075 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL652674 1.00 SLC6A4 (0.78) SLC6A4SLC6A2SLC6A3DPP4DPP7
SCHEMBL7957756 1.00 SLC6A4 (0.78) SLC6A4SLC6A2SLC6A3DPP4DPP7
SCHEMBL2295017 0.89 SLC6A4 (0.62) SLC6A4SLC6A2SLC6A3NMT1PPARG
SCHEMBL2295009 0.89 SLC6A4 (0.62) SLC6A4SLC6A2SLC6A3NMT1PPARG
Hydrochloric Acid SCHEMBL6478645 0.87 SLC6A4 (0.60) SLC6A4SLC6A2SLC6A3PPARGPPARA
Hydrochloric Acid SCHEMBL6478641 0.87 SLC6A4 (0.60) SLC6A4SLC6A2SLC6A3PPARGPPARA
Trifluoroacetic Acid SCHEMBL4544157 0.86 SLC6A4 (0.58) SLC6A4SLC6A2SLC6A3DPP4DPP7
SCHEMBL9921946 0.82 SLC6A4 (0.78) SLC6A4SLC6A2SLC6A3DPP4DPP7
SCHEMBL3441646 0.82 SLC6A4 (0.78) SLC6A4SLC6A2SLC6A3DPP4DPP7
SCHEMBL18607979 0.81 SLC6A4 (0.69) SLC6A4SLC6A2SLC6A3DPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2681215-B1 SERINE/THREONINE KINASE INHIBITORS ARRAY BIOPHARMA INC (US) 2015-04-22 EP claimed
EP-4732286-A2 COMPOSITIONS AND METHODS FOR ENCRYPTING, STORING, AND DECRYPTING INFORMATION IN OLIGOMERS Board of Regents, The University of Texas System (US) 2026-04-29 EP disclosed
EP-4269400-B1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS MOLECURE SA (PL) 2025-07-09 EP disclosed
US-12325701-B2 YKL-40 inhibitors and their therapeutic MOLECURE S.A. (PL) 2025-06-10 US disclosed
WO-2025058677-A2 COMPOSITIONS AND METHODS FOR ENCRYPTING, STORING, AND DECRYPTING INFORMATION IN OLIGOMERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-03-20 WO disclosed
US-20230348516-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS MOLECURE S.A. (PL) 2023-11-02 US disclosed
US-20230348516-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS MOLECURE S.A. (PL) 2023-11-02 US disclosed
US-20230348516-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS MOLECURE S.A. (PL) 2023-11-02 US disclosed
EP-4269400-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS Molecure SA (PL) 2023-11-01 EP disclosed
EP-4269400-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS Molecure SA (PL) 2023-11-01 EP disclosed
US-6353006-B1 TREATMENT OF BONE DISORDERS, OSTEOPOROSIS AND HEALING AGENT BAYER CORPORATION 2002-03-05 US disclosed
EP-1092435-A1 REMEDIES FOR DIABETES KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-04-18 EP disclosed
WO-2001009127-A1 BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE AVENTIS PHARMA S.A. (FR) 2001-02-08 WO disclosed
US-5942387-A Combinatorial process for preparing substituted thiophene libraries ELI LILLY AND COMPANY (US) 1999-08-24 US disclosed
EP-0825164-A2 Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides ELI LILLY AND COMPANY (US) 1998-02-25 EP disclosed
EP-0818431-A1 Scavenger assisted combinatorial process for preparing libaries of secondary amine compounds ELI LILLY AND COMPANY (US) 1998-01-14 EP disclosed
EP-0816309-A1 Scavenger assisted combinatorial process for preparing libraries of urea and thiourea compounds ELI LILLY AND COMPANY (US) 1998-01-07 EP disclosed
US-5466687-A Anticholesterol agents DR. KARL THOMAE GMBH (DE) 1995-11-14 US disclosed
EP-0596326-B1 Arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes, their salts, medicaments containing the same, use thereof and precesses for their production THOMAE GMBH DR K (DE) 1995-08-23 EP disclosed
EP-0596326-A1 Arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes, their salts, medicaments containing the same, use thereof and precesses for their production Dr. Karl Thomae GmbH (DE) 1994-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348516-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS CHI3L1, CHI3L2, CHIA SLC6A4 4724/4885SLC6A2 4847/4885SLC6A3 4837/4885
US-12325701-B2 YKL-40 inhibitors and their therapeutic CHI3L1, CHI3L2, CHIA SLC6A4 4021/4885SLC6A2 4753/4885SLC6A3 4725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.