Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776363 | 0.91 | GABRA1 (0.60) | GABRA1GABRA5 | |
| SCHEMBL1777918 | 0.90 | GABRA5 (0.71) | GABRA1GABRA5 | |
| SCHEMBL1778273 | 0.89 | GABRA5 (0.61) | GABRA1GABRA5 | |
| SCHEMBL2928471 | 0.89 | GABRA1 (0.76) | GABRA1GABRA5 | |
| SCHEMBL1776592 | 0.89 | ITGA5 (0.61) | GABRA1GABRA5 | |
| SCHEMBL108079 | 0.88 | GABRA5 (0.70) | GABRA1GABRA5 | |
| SCHEMBL107284 | 0.86 | GABRA1 (0.62) | GABRA1GABRA5 | |
| SCHEMBL286529 | 0.84 | GABRA5 (0.54) | GABRA5 | |
| SCHEMBL287532 | 0.84 | GABRA5 (0.52) | GABRA5 | |
| SCHEMBL1777013 | 0.84 | GABRA5 (0.59) | GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943619-B2 | Isoxazolo-pyridazine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2011-05-17 | — | — | US | disclosed |